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THE PICOWER INSTITUTE

Massachusetts Institute of Technology
43 Vassar Street, Bldg. 46-1303
Cambridge, MA 02139
(+1) 617-324-0305
(+1) 617-452-2588

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A collage of some of the innovations

Innovations & Inventions

Explore many of the new technologies, potential treatments, unique research models, startup companies and organizations, and other innovations that Picower Institute faculty members have helped to introduce during their careers, working with collaborators ranging from mentors to students.

GENUS

A cartoon of microglia, stimulated by gamma waves, gobbling up amyloid plaque

IGF1

A schematic shows the role of IGF-1 in synaptic function

SCOUT

An organoid appears as an elongated, colorful, blob shape with large oblong holes in a few places

TRAP

Stochastic electrotransport

EEG monitoring of anesthesia

Arbaclofen for Fragile X

Huntington's Model Fruit Flies

Bright yellow wisps indicate aggregated mutant huntingtin protein.

Optical Quantal Imaging

Open Ephys

A round circuit board labeled Open Ephys

Feedback-driven stimulation

A circuit diagram of the bandpass filter for feedback

Whole-brain tracking in moving animals

A white microscope with many wires and attachments sits on a black table

GSK-alpha inhibitor for Fragile X

A series of black lines, mostly arrayed as three hexagons in a row, with letters H and N in chemically meaningful positions

ELAST

Between a pair of two blue glvoes a shiny clear sheet of brain tissue is pulled taut

Genome-wide genetic screening in the mammalian brain

A scgenatuc showing how genetic material is loaded into viruses that are then injected into a mouse brain

Multi-color two-photon microscopy

A neuron shows synapses of different colors

SplitSage

The splitsage logo is paired wih a gazing eye.

CLARITY

A clarified brain with many different types of cells stained different colors

MAP

Lab-engineered human blood-brain barrier

On a black backgound a 3D-looking loop of gray vessel is covered in green blotches

Treating Amblyopia

A black and white close up photo of an eye

"Reanimation"

A slide shows EEG waves of a rat while awake, anesthetized and then reanimated with Ritalin

HDAC2 Inhibition

Schematics show HDAC2 and SP3 combining to inhibit memory

SWITCH

A series of panels shows different things labeled with switch

Advanced Three-Photon Microscopy

A series of images shows a full vertical shaft of an organoid as well as slices at varying depths.

The p25 mouse

Slice through a mouse brain shows huge ventricles opened up by neurodegeneration in a p25 mouse

Altering circuits for mood disorders

Head silhouette with amygdala

Former Member Innovations and Inventions

  • View innovations and inventions by former Picower faculty

Massachusetts Institute of Technology
43 Vassar Street, Bldg. 46-1303
Cambridge, MA 02139
(+1) 617-324-0305
(+1) 617-452-2588

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From: https://picower.mit.edu/research/innovations-inventions