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Volunteer for research

Get involved! See below for ways to participate in ongoing studies at the Picower Institute and Aging Brain Initiative.


Application of Sensory Stimulation for Gamma Frequency Entrainment

 IRB#1712179268

The Tsai Laboratory is looking for healthy women volunteers ages 55-85 to participate in a study looking at how light and sound effect the brain. You will be asked to come to our laboratory for a 1-time visit lasting approximately 3.5 hours. During the first hour, you will complete memory testing. For the remaining 2.5 hours, you will be asked to complete an electroencephalogram (EEG) recording where we will record your brain wave activity. You will be asked to do activities including sitting with your eyes open or closed or watching a movie. All participants will be compensated for their time.

If interested, please contact Danielle Stark (dstark@mit.edu).


2 Week Non-Invasive Light and Sound Study of the Brain

IRB #1808497067

The Tsai Laboratory is looking for healthy volunteers for a study looking at the effect of a non-invasive device delivering light and sound over a 14-day period.

This Study Involves:

  • Two visits to MIT each lasting approximately 6 hours.
  • Two weeks of daily at home visual and auditory stimulation for 60 minutes every day. 
  • Pre- and post- assessments in a lab setting at MIT including EEG recording, fMRI and cognitive health evaluations.
  • One follow-up phone call 7 days after the completion of the daily stimulation
  • Financial compensation of up to $300 upon completion of the study

Are You Eligible? 

  • Be between the ages of 55-100
  • Have no history of cognitive impairment, dementia, seizures, epilepsy, stroke or other significant neurological disorders. 
  • Have no history of traumatic brain injury or brain surgery
  • Not currently taking psychiatric medications (e.g. antidepressants, antipsychotics, etc.) nor medications for the treatment of dementia
  • No history of visual or hearing impairment (ex. cataracts or hearing aids)

If interested, please contact Danielle Stark (dstark@mit.edu) for more information.


Acute Treatment of Alzheimer’s disease with Gamma Frequency Stimulation

IRB # 1902706647

The Tsai Laboratory is actively recruiting patients who have early to mild stage Alzheimer's disease to participate in our study that aims to evaluate the feasibility and safety of using light and sound sensory stimulation in people diagnosed with early to mild Alzheimer’s disease.

This Study Involves:

  • One visit to MIT lasting approximately 6 hours.
  • Cognitive health evaluations, EEG recording, short exposures to our light and sound stimulation in various combinations and Pre- and post- assessments in a lab setting at MIT.
  • Financial compensation of up to $75 upon completion of the study

Are You Eligible? 

  • Be between the ages of 55-100
  • Clinical diagnosis of early to mild Alzheimer’s disease*
  • Have no history of seizures, epilepsy, stroke, or other significant neurological disorders.
  • Not currently prescribed memantine for memory difficulties (ex. Namenda, Namenda Titration Pak, and Namenda XR)
  • Local to the Greater Boston area

Please note that participation in this one visit does not guarantee eligibility in future clinical trials conducted at MIT but also does not exclude anyone from participating.

If interested, please contact Danielle Stark (dstark@mit.edu) for more information.


Chronic Treatment of Alzheimer's disease with Gamma Frequency Stimulation

IRB # 1903763319

The Tsai Laboratory is actively recruiting patients who have early to mild stage Alzheimer's disease to participate in our study that aims to evaluate the feasibility and safety of using chronic light and sound sensory stimulation as a therapy for Alzheimer’s disease. At the first session at MIT, participants will be asked to complete a blood draw, functional magnetic resonance imaging scan (fMRI), memory testing, and be treated with a device that delivers light and sound. We will measure your brain waves with an electroencephalogram (EEG). These procedures will be repeated after 6 months and 1-year follow-up visits.  In between visits, all participants will complete daily at home visual and auditory stimulation for 60 minutes every day. 

 

Are You Eligible? 

  • Be between the ages of 55-100
  • Clinical diagnosis of early to mild Alzheimer’s disease*
  • Have no history of seizures, epilepsy, stroke, or other significant neurological disorders.
  • Not currently prescribed memantine for memory difficulties (ex. Namenda, Namenda Titration Pak, and Namenda XR)
  • Local to the Greater Boston area for the duration of the study

 

If interested, please contact Danielle Stark (dstark@mit.edu) for more information.


Research Study Volunteers Needed

IRB # 1804343699A001:

The Neuroscience Statistics Research Laboratory is looking for healthy volunteers to participate in a study about physiological signals. Electrodermal activity (EDA) measures sweat gland activity in the skin. Heartrate variability is a normally occurring phenomenon in all people. EEG measures brain activity. All you will be asked to do is come to our lab and spend about 3 hours with several electrodes attached to your non-dominant hand and wrist, a few standard adhesive medical electrodes on the torso and forehead, and a belt around the torso to collect data. During the first hour, you can bring something to read or watch; we just ask that you not sleep or type on a computer using the hand with electrodes. During the second hour, we will ask you to do several tasks intended to cause changes in your “fight-or-flight” response, like breathing along with a metronome, standing and sitting repeatedly, looking at specific pictures, gripping and holding a dynamometer at a certain force, dipping your hand in a container of ice water, and being strapped to a tilt table. You will be reimbursed for your time with a gift card for $10 at the end.

If interested, please contact Sandya Subramanian (sandya@mit.edu).


 

Massachusetts Institute of Technology
43 Vassar Street, Bldg. 46-1303
Cambridge, MA 02139
(+1) 617-324-0305
(+1) 617-452-2588