Two black panels on a white background show sections of brain. One glows with neurons colored green. The other panel glows with neurons colored red.
August 5, 2022
When a task adds more steps, this circuit helps you notice
A ball of electric blue tangly cells is overlaid by the siilhouette of an array of long wires that terminte in little round balls
August 4, 2022
How microglia contribute to Alzheimer’s disease
A horizontal strip of five panels shows successive zooming in on a section of an organoid. In each level of zoom traditional staining is compared with THG imaging.
July 29, 2022
Advanced imaging reveals mired migration of neurons in Rett syndrome lab models
A man in a suit on a city street runs to catch up to a red bus at a stop.
July 28, 2022
Sprint then stop? Brain is wired for the math to make it happen
July 20, 2022
New findings reveal how neurons build and maintain their capacity to communicate

When a task adds more steps, this circuit helps you notice

August 5, 2022
Research Findings
By tracking feedback during tasks, the anterior cingulate cortex notices when a new step has become necessary and signals the motor cortex to adjust

How microglia contribute to Alzheimer’s disease

August 4, 2022
Research Findings
A breakdown of lipid metabolism in these brain cells promotes inflammation and interferes with neuron activity, a new study finds

Advanced imaging reveals mired migration of neurons in Rett syndrome lab models

July 29, 2022
Research Findings
Using organoids to model early development, researchers used an emerging microscopy technology to see that new neurons struggled to reach their developmental destination

Sprint then stop? Brain is wired for the math to make it happen

July 28, 2022
Research Findings
To ensure a quick halt, brain circuit architecture avoids a slow process of integration in favor of quicker differentiation, study finds

New findings reveal how neurons build and maintain their capacity to communicate

July 20, 2022
Research Findings
Nerve cells regulate and routinely refresh the collection of calcium channels that enable them to send messages across circuit connections

For high schoolers, summer starts with extra exposure to biomedical science

June 23, 2022
Picower People
Just before school was out for summer, high school students from Everett and Lawrence toured life sciences research labs at MIT to get information and inspiration

How the brain responds to surprising events

June 1, 2022
Research Findings
Unexpected outcomes trigger release of noradrenaline, which helps the brain focus its attention and learn from the event

NIH award to help Heiman unearth roots of Huntington’s pathology

May 26, 2022
New Research
Research Program Award will fund studies to find early triggers of disease progression

Brown wins share of 2022 Gruber Neuroscience Prize

May 17, 2022
Picower People
Emery N. Brown and three other scientists recognized for advancing statistical, theoretical analyses of neuroscience data

Circuit model may explain how deep brain stimulation treats Parkinson’s disease symptoms

May 16, 2022
Research Findings
Stimulation of subthalamic nucleus interrupts a cycle of runaway beta-frequency rhythms and restores ability of interneurons to regulate rhythms in the brain’s striatum, improving movement, study suggests

Anesthetic drastically diverts the travels of brain waves

April 27, 2022
Research Findings
Under propofol general anesthesia very slow frequency traveling waves transform and dominate, redirecting and disrupting the higher frequency traveling waves associated with conscious function

Circuit that focuses attention brings in wide array of inputs

April 21, 2022
Research Findings
With a comprehensive map of the wiring, researchers can now discern what information flows into the circuit to enable a key brain function