A security guard views a bank of eight monitors on his desk. The perspective of the image is from behind the security guard so that the various parts of a building's interior is visible on the monitors.
October 20, 2025
Like radar, a brain wave sweeps a cortical region to read out information held in working memory
Six panels show circular arrangements of each individual cell type in a miBrain culture, stained in cyan. The cell types are Pericytes, Astrocytes, Endothelial Cells, Neurons, Oligodendroglia, and Microglia
October 17, 2025
MIT invents human brain model with six major cell types to enable personalized disease research, drug discovery
An array of six panels shows different views of a long, thin, spiny structure that closely resembles a bumpy twig. Each is stained bright green and the degree of bumpiness varies along each one.
October 16, 2025
Study finds circular RNA helps drive brain development
Two stacked electron microscope images show a synapse. Above a small, river-like gap is a dark T shape among many tiny bubble-like circles. In the bottom image the T shape is much bigger than in the upper image.
October 14, 2025
Neural activity helps circuit connections mature into optimal signal transmitters
The almond shape of the amygdala is composed of cells stained red (on the left) and green (on the right).
September 29, 2025
Many Mechanisms of Mood

When life supplies motivation to do research, a summer at Picower can provide the experience

July 21, 2025
Picower People
For undergraduates around the country who are interested in studying neuroscience but don't have enough opportunities at their home institutions, Picower Institute labs can provide a way to do cutting edge research and gain exposure to a possible future i

Connect or reject: Extensive rewiring builds binocular vision in the brain

July 1, 2025
Research Findings
A first-of-its-kind study in mice reveals that neurons add and shed synapses at a frenzied pace during development to integrate visual signals from the two eyes.

As textbook’s 5th edition hits shelves, Bear reflects on introducing many 1,000s of students to neuroscience

June 18, 2025
Picower People
With an emphasis on approachability, “Neuroscience: Exploring the Brain” enters its fourth decade as the text of undergraduate neuroscience classes worldwide

Autism advances

June 16, 2025
Research Feature
Rooted in fundamental curiosity about how the brain works, Picower scientists continue to break new ground in understanding autism and devising treatment strategies

Aging Brain Initiative seed grants fund five new projects to address neurodegenerative disease

June 9, 2025
New Research
Campuswide collaboration sparks new research to develop assistive technology, enhance interventions, decipher brain biochemistry, advance big data analysis, and assess the public’s understanding of dementia risk and protective factors.

The how and why of the brain’s division across hemispheres

May 12, 2025
Research Findings
Why does the brain split visual spatial perception between its hemispheres? A new review examines the advantages and trade-offs, and how the brain ultimately makes vision feel seamless.

Different anesthetics, same result: unconsciousness by shifting brainwave phase

May 12, 2025
Research Findings
MIT study finds that an easily measurable brain wave shift may be a universal marker of unconsciousness under anesthesia

Dopamine signals when a fear can be forgotten

April 28, 2025
Research Findings
Study shows how a dopamine circuit between two brain regions enables mice to extinguish fear after a peril has passed.

In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity

April 24, 2025
Research Findngs
Study provides new evidence that sensory stimulation of gamma-frequency brain rhythm may promote broad-based restorative neurological health response.

MIT Down syndrome researchers work on ways to ensure a healthy lifespan

April 24, 2025
Picower Events
An Alana Down Syndrome Center webinar, co-sponsored by the Massachusetts Down Syndrome Congress, presented numerous MIT studies that all share the goal of improving health throughout life for people with trisomy 21.

With Searle Scholar award, Fan will study serotonin role in memory

April 22, 2025
Picower People
Assistant Professor Linlin Fan will apply her lab’s precise “all-optical” techniques to study how serotonin might influence plasticity in memory, and whether psychedelics affect that.

In kids, EEG monitoring of consciousness safely reduces anesthetic use

April 21, 2025
Research Findings
Clinical trial finds several outcomes improved for young children when an anesthesiologist observed their brain waves to guide dosing of sevoflurane during surgery.