A member of a surgical staff holds a mask on the face of an unconscious patient in an operating room
March 17, 2026
Three anesthesia drugs all have the same effect in the brain, MIT researchers find
Li-Huei Tsai stands at a podium embossed with an MIT logo. In the foreground is an attentive audience. In the background is the Picower Institute logo
March 11, 2026
After 16+ years leading Picower Institute, Li-Huei Tsai will sharpen focus on research, teaching
Two panels show blue cells surrounded by thin green outlines. The outlines are much more consistent and prevalent in the image on the left, which is labeled as the wild type, than on the right which is labeled Rett syndrome.
February 25, 2026
In Rett syndrome, leaky brain blood vessels traced to microRNA
a series of small blocky spots of color appear in the aggregate to make up the shape of a worm as it stretches horizonally across a black background
February 24, 2026
As worms and jellyfish wriggle, new AI tools track their neurons
Linlin Fan stands in her lab with microscope equipment in the foreground.
February 17, 2026
Sloan Fellowship will help Fan advance technology to study how brain circuits change amid learning

Focus on Fats

December 17, 2025
Research Feature
A Picower Institute lab is on a mission to discover how cells mishandle lipid molecules in Alzheimer’s disease and is using that knowledge to develop treatments.

Prefrontal cortex reaches back into the brain to shape how other regions function

November 25, 2025
Research Findngs
A new MIT study illustrates how areas within the brain’s executive control center tailor their messages in specific circuits with other brain regions to influence them with information about behavior and internal feelings.

Too sick to socialize: How the brain and immune system promote staying in bed

November 25, 2025
Research Findngs
MIT researchers have discovered how an immune system molecule triggers neurons in a specific brain circuit to shut down social behavior in mice modeling infection.

RNA editing study finds many ways for neurons to diversify

November 20, 2025
Research Findngs
When MIT neurobiologists tracked how more than 200 motor neurons in fruit flies each edited their RNA, they cataloged hundreds of target sites and widely varying editing rates. Scores of edits altered proteins involved in neural communication and function

MIT study shows how vision can be rebooted in adults with amblyopia

November 19, 2025
Research Findngs
Temporarily anesthetizing the retina briefly reverts the activity of the visual system to that observed in early development and enables growth of responses to the amblyopic eye, new research shows

Brain waves’ analog organization of cortex enables cognition and consciousness, MIT professor proposes at SfN

November 15, 2025
Picower People
On neuroscience’s big stage Nov. 15, MIT Professor Earl K. Miller proposed that thought and consciousness emerge from the fast and flexible organization of the cortex produced by the analog computations of brain waves.

Q&A: Picower researchers join effort to investigate the ‘Biology of Adversity’

November 3, 2025
New Research
Assistant Professor Sara Prescott and Research Affiliate Ravikiran Raju are key collaborators in a new Broad Institute research project to better understand physiological and medical effects of acute and chronic life stressors.

After distractions, rotating brain waves may help thought circle back to the task

November 3, 2025
Research Findngs
To get back on track after a distraction, the cortex appears to employ a rotating traveling wave, a new study by MIT neuroscientists finds.

Symposium examines the neural circuits that keep us alive and well

October 28, 2025
Picower Events
Seven speakers from around the country convened at MIT to describe some of the latest research on the neural mechanisms that we need to survive.

Small study suggests 40Hz sensory stimulation may benefit some Alzheimer’s patients for years

October 27, 2025
Research Findngs
Five volunteers continued receiving 40Hz stimulation for around two years after an early-stage MIT clinical study. Those with late-onset Alzheimer’s performed significantly better on assessments than comparable Alzheimer’s patients outside the trial

MIT-based team advances to semi-finals of Gates-funded competition to apply ’agentic’ AI to studying Alzheimer’s

October 21, 2025
New Research
“FINGERPRINT” proposes to use AI to link discovery, prevention, therapy by reasoning across multiple biological and clinical data sets.

Like radar, a brain wave sweeps a cortical region to read out information held in working memory

October 20, 2025
Research Findngs
When spotting what’s changed from one scene to the next, performance will depend on a low-frequency “theta” brain wave that scans the mental image, a new MIT study shows.