A 3D cartoon of a mouse jumping around on a landscape of white hexagonal pillars. The mouse's trajectory through time is noted with a wiggly blue line. The mouse wears electronics on the back of its head and a small thin wire comes up out of them.
November 13, 2024
Open technology platform enables new versatility for neuroscience research with more naturalistic behavior
A cartoon shows a head in profile split between a gray region at the front and a green region at the back. In the back is a bell and progressively larger dotted white circles propagate outward from the bell toward the front of the head.
October 7, 2024
The way sensory prediction changes under anesthesia tells us how conscious cognition works
A view of a surgery in progress. Surgeons wearing blue gowns hold a scalpel and scissors just above an opening in the dressing of a patient who is lying on a table. Blurred in the foreground is a tray of other surgical instruments.
September 23, 2024
Research quantifying “nociception” could help improve management of surgical pain
A diagram shows hundreds of dots interconnected by gray lines. Many of the dots show combinations of different colors, denoting which serotonin receptors they express.
September 6, 2024
Better living through brain chemistry
Two panels show the emergence of seizures. Calm, narrow dark blue squiggles representing a tight range of low voltages at various currents explode into vibrant, wide squiggles with warmer colors as current and voltage increases at a broadening range of frequencies.
August 21, 2024
Study assesses seizure risk from stimulating thalamus

HHMI honor will advance Flavell’s studies of how internal brain states arise and affect behavior

July 23, 2024
Picower People
In animals from worms to humans, feelings and drives such as hunger or sleepiness influence behavior. With flexible, long-term support as a newly named HHMI Investigator, Steve Flavell will advance his lab’s studies of exactly how that happens.

Study reveals how an anesthesia drug induces unconsciousness

July 15, 2024
Research Findings
Propofol, a drug commonly used for general anesthesia, derails the brain’s normal balance between stability and excitability.

Fellowship supports student’s work to advance Alzheimer’s research and equity

July 9, 2024
Picower People
With strong personal motivation and up to three years of support from the HHMI Gilliam Fellows Program, graduate student Mingus Rae Zoller will probe mysteries of Alzheimer’s and its possible treatment.

Award will enable detailed study of an organism that constantly adds new neurons

July 8, 2024
Picower People
With an eye on implications for regenerative medicine, Assistant Professor Brady Weissbourd will use the support of being named a Searle Scholar to study how jellyfish excel at building and regenerating their neural networks.

Fellowship enables study of how the brain makes memories of places

July 1, 2024
Picower People
With a new Klingenstein-Simons Fellowship in Neuroscience, Assistant Professor Linlin Fan will seek to strengthen understanding of how neural connections change to encode memories of specific locations.

Pew award will fund study of neural role in respiratory disease

June 18, 2024
Picower People
As a newly named Pew Biomedical Scholar, Assistant Professor Sara Prescott and her lab plan to test whether and how neurons have a role in airway remodeling, which goes awry in many diseases.

Technologies enable 3D imaging of whole human brain hemispheres at subcellular resolution

June 13, 2024
Research Findings
A suite of three innovations by an MIT-based team enables high-throughput imaging of human brain tissue at a full range of scales and mapping connectivity of neurons at single cell resolution.

Consciousness

June 12, 2024
Research Feature
Emerging evidence shows how brain waves help to knit our internal thoughts and external awareness together into an organized, unified whole

With programmable pixels, novel sensor improves imaging of neural activity

June 7, 2024
Research Findings
New camera chip design allows for optimizing each pixel’s timing to maximize signal to noise ratio when tracking real-time visual indicator of neural voltage

Microscope system sharpens scientists’ view of neural circuit connections

June 4, 2024
Research Findings
A newly described technology improves the clarity and speed of using two-photon microscopy to image synapses in the live brain

Study models how ketamine’s molecular action leads to its effects on the brain

May 20, 2024
Research Findings
New research addresses a gap in understanding how ketamine’s impact on individual neurons leads to pervasive and profound changes in brain network function.

How the brain is flexible enough for a complex world (without being thrown into chaos)

May 13, 2024
Research Findings
Many neurons exhibit “mixed selectivity.” They can integrate multiple inputs and participate in multiple computations. Mechanisms such as oscillations and neuromodulators recruit their participation and tune them to focus on the relevant information.