MIT neuroscientists have found that either of two genetic mutations that cause Rett syndrome undermine the structural integrity of developing blood vessels. By showing that the problem derives from overexpression of a microRNA, the new study points to a p

Three new neural network-based tools enable fast, accurate alignment and annotation of images even in very wiggly subjects. The tools might offer a way to automate cell tracking in other imaging datasets, too.

Linlin Fan uses innovative optical tools to precisely investigate how connections change among neurons during memory formation. With Sloan Foundation support, she plans to give the technology a significant upgrade

A collaboration centered at MIT discovered that mice modeling the autism spectrum disorder fragile X syndrome exhibit the same pattern of differences in low-frequency waves as human patients, identifying a new biomarker for treatment studies

Filled with vitally important neural fibers, the brainstem has been hard for brain imaging technologies to dissect. New software reliably and finely resolves eight distinct nerve bundles in live diffusion MRI scans, revealing signs of injury or disease

A new MIT study finds that somatostatin-expressing neurons follow a unique trajectory when forming connections in the brain’s visual cortex that may help establish the conditions needed for sensory experience to refine circuits.

A new ‘biomimetic’ model of brain circuits and function at multiple scales produced naturalistic dynamics and learning, and even identified curious behavior by some neurons that had gone unnoticed in real-brain data.

In a new study, MIT researchers tested their theory of Spatial Computing, which holds that the brain recruits and controls ad hoc groups of neurons for cognitive tasks by applying brain waves to patches of the cortex.

A Picower Institute lab is on a mission to discover how cells mishandle lipid molecules in Alzheimer’s disease and is using that knowledge to develop treatments.

MIT researchers have discovered how an immune system molecule triggers neurons in a specific brain circuit to shut down social behavior in mice modeling infection.

A new MIT study illustrates how areas within the brain’s executive control center tailor their messages in specific circuits with other brain regions to influence them with information about behavior and internal feelings.

When MIT neurobiologists tracked how more than 200 motor neurons in fruit flies each edited their RNA, they cataloged hundreds of target sites and widely varying editing rates. Scores of edits altered proteins involved in neural communication and function