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… pathways Neuroimmune interactions lipid metabolism Neuronal DNA damage neurodegeneration … cells, such as levels of RNA which is transcribed from DNA, so that the cell’s functions and roles of in the biology …

… (scRNA-seq). Almost all cells in an organism have the same DNA, but each type of cell becomes distinct in its form and … Alzheimer’s disease risk genes or experiencing age-related DNA damage. In some of her most recent studies, she and …

… it might be perhaps more of a secondary response to neural damage,” Heiman said. Similarly, in the late 1990s as Picower … When encoding memories, neurons normally snap open their DNA for quick gene expression, Tsai’s lab has found that over … screen therefore revealed which genes were essential for neuronal survival. The lab then also did the screen in mice …

… disease progresses over time and how it is associated with DNA damage. In work to determine the key cell types that allow … including a healthier state of microglia and reduced DNA damage. Gwyneth Welch and Liwang Liu also presented …

… biological tissue, allowing them to visualize proteins, DNA, and other molecules within cells, and to map the … studied unless steps are taken to preserve the tissue from damage. Chung and other researchers have previously developed … blocks of proteins), as well as other molecules such as DNA and RNA. The flexible backbone allows the epoxides to …

… therapy, which involves synthesizing “designer DNA drugs” that can intercede to compensate for a genetic … back into action, reducing amyloid plaques and preventing damage to neurons. Colonna’s Washington University colleague … For instance, he’s found that the protein is necessary for neuronal hyperexcitability to emerge in Alzheimer’s disease …

… epigenetic gene regulation, enzyme pathways and repair of DNA damage. Tsai and collaborators have also uncovered substantial evidence that impaired neuronal synchrony may underlie Alzheimer’s progression, an …

… know exactly how that may contribute to the devastating damage to neurons that characterizes both ALS and the related … in gene expression and various factors, such as DNA accessibility, that can cause gene transcription to vary, …