Monday, May 18
… Study finds that aging neurons accumulate DNA damage May 18, 2020 Research Findings Reactivating an enzyme … decline in mice. epigenetics neurodegeneration aging Neuronal DNA damage …
Tuesday, Jul 06
… Memory making involves extensive DNA breaking July 6, 2021 Research Findings To quickly … and cell types than previously realized, a new study shows Neuronal DNA damage epigenetics astrocytes …
… Neuroimmune interactions myelination ApoE lipid metabolism Neuronal DNA damage 46-4235 617-324-1658 lhtsai.mit@gmail.com …
Monday, Dec 17
… biological tissue, allowing them to visualize proteins, DNA, and other molecules within cells, and to map the … studied unless steps are taken to preserve the tissue from damage. Chung and other researchers have previously developed … blocks of proteins), as well as other molecules such as DNA and RNA. The flexible backbone allows the epoxides to …
Monday, Oct 28
… disease progresses over time and how it is associated with DNA damage. In work to determine the key cell types that allow … including a healthier state of microglia and reduced DNA damage. Gwyneth Welch and Liwang Liu also presented …
Monday, Oct 07
… accessible state for expression, compared to the same DNA in unenriched animals. They then showed that by … inhibiting proteins responsible for locking down DNA, called HDACs, they could mimic enrichment’s benefits and … that in many AD models, neural DNA showed the severe damage of double-strand breaks (DSBs) so the lab set out to …
Thursday, Sep 24
… therapy, which involves synthesizing “designer DNA drugs” that can intercede to compensate for a genetic … back into action, reducing amyloid plaques and preventing damage to neurons. Colonna’s Washington University colleague … For instance, he’s found that the protein is necessary for neuronal hyperexcitability to emerge in Alzheimer’s disease …
Wednesday, Jan 23
… epigenetic gene regulation, enzyme pathways and repair of DNA damage. Tsai and collaborators have also uncovered substantial evidence that impaired neuronal synchrony may underlie Alzheimer’s progression, an …
Tuesday, Oct 05
… know exactly how that may contribute to the devastating damage to neurons that characterizes both ALS and the related … in gene expression and various factors, such as DNA accessibility, that can cause gene transcription to vary, …
… in Tauopathies 4:00 PM - 5:00 PM Presentation 044.04 / D7 Neuronal hyperactivity and DNA damage in tau P301S mouse model *L. LIU , P.-C. PAO, L. A. …
