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… contain and transport the neurotransmitters that enable neuronal communication. To improve conduction of their … the team saw ominous effects on lipid metabolism, DNA damage, and mitochondrial function in neurons. Similar …

… pathways Neuroimmune interactions lipid metabolism Neuronal DNA damage neurodegeneration … cells, such as levels of RNA which is transcribed from DNA, so that the cell’s functions and roles of in the biology …

… (scRNA-seq). Almost all cells in an organism have the same DNA, but each type of cell becomes distinct in its form and … Alzheimer’s disease risk genes or experiencing age-related DNA damage. In some of her most recent studies, she and …

… it might be perhaps more of a secondary response to neural damage,” Heiman said. Similarly, in the late 1990s as Picower … When encoding memories, neurons normally snap open their DNA for quick gene expression, Tsai’s lab has found that over … screen therefore revealed which genes were essential for neuronal survival. The lab then also did the screen in mice …

… disease progresses over time and how it is associated with DNA damage. In work to determine the key cell types that allow … including a healthier state of microglia and reduced DNA damage. Gwyneth Welch and Liwang Liu also presented …

… therapy, which involves synthesizing “designer DNA drugs” that can intercede to compensate for a genetic … back into action, reducing amyloid plaques and preventing damage to neurons. Colonna’s Washington University colleague … For instance, he’s found that the protein is necessary for neuronal hyperexcitability to emerge in Alzheimer’s disease …

… epigenetic gene regulation, enzyme pathways and repair of DNA damage. Tsai and collaborators have also uncovered substantial evidence that impaired neuronal synchrony may underlie Alzheimer’s progression, an …