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… diseases. Cdk5 neurodegeneration Neuroimmune interactions Neuronal DNA damage dementia … they found dramatic reductions in neurodegeneration and DNA damage in the brain. These mice also showed improvements …

… pathways Neuroimmune interactions lipid metabolism Neuronal DNA damage neurodegeneration … cells, such as levels of RNA which is transcribed from DNA, so that the cell’s functions and roles of in the biology …

… it might be perhaps more of a secondary response to neural damage,” Heiman said. Similarly, in the late 1990s as Picower … When encoding memories, neurons normally snap open their DNA for quick gene expression, Tsai’s lab has found that over … screen therefore revealed which genes were essential for neuronal survival. The lab then also did the screen in mice …

… Neuroimmune interactions myelination ApoE lipid metabolism Neuronal DNA damage 46-4235 617-324-1658 lhtsai.mit@gmail.com …

… disease progresses over time and how it is associated with DNA damage. In work to determine the key cell types that allow … including a healthier state of microglia and reduced DNA damage. Gwyneth Welch and Liwang Liu also presented …

… accessible state for expression, compared to the same DNA in unenriched animals. They then showed that by  … inhibiting proteins responsible for locking down DNA, called HDACs, they could mimic enrichment’s benefits and … that in many AD models, neural DNA showed the severe damage of double-strand breaks (DSBs) so the lab set out to …

… biological tissue, allowing them to visualize proteins, DNA, and other molecules within cells, and to map the … studied unless steps are taken to preserve the tissue from damage. Chung and other researchers have previously developed … blocks of proteins), as well as other molecules such as DNA and RNA. The flexible backbone allows the epoxides to …

… therapy, which involves synthesizing “designer DNA drugs” that can intercede to compensate for a genetic … back into action, reducing amyloid plaques and preventing damage to neurons. Colonna’s Washington University colleague … For instance, he’s found that the protein is necessary for neuronal hyperexcitability to emerge in Alzheimer’s disease …