… Massachusetts Institute of Technology Research Areas mGluR5 , LTD , LTP , monocular deprivation , habituation , … by activation of metabotropic glutamate receptor 5 (mGluR5) and requires immediate translation of mRNAs at … discovered that protein synthesis (and LTD) downstream of mGluR5 is exaggerated in the mouse model of fragile X (FX). …