Members of Picower labs are presenting research at Neuroscience 2021 in a wide range of areas. Browse below for presentation titles and authors, organized by day and session.
Monday, Nov. 8, 2021
Session P261 Parkinson's Disease: Subthalamic Nucleus and Deep Brain Stimulation
1:15 PM - 2:15 PM
Presentation P261.06 Deep brain stimulation in the subthalamic nucleus for Parkinson’s disease can restore dynamics of striatal networks
*E. M. ADAM1, E. N. BROWN1, N. J. KOPELL2, M. M. MCCARTHY2;
1MIT, Cambridge, MA; 2Boston Univ., Boston, MA
Tuesday, Nov. 9, 2021
Session P842 Dynamics of Memory Representations
8:30 AM - 9:30 AM
Presentation P842.03 Latent learning drives sleep-dependent plasticity in distinct CA1 subpopulations
*W. GUO, J. J. ZHANG, J. P. NEWMAN, M. A. WILSON;
The Picower Inst. for Learning and Memory, MIT, Cambridge, MA
Session P099 Vesicle Docking, Fusion, and Recycling
- 9:00 AM - 10:00 AM
Presentation P099.03 RNA editing of the synaptic vesicle fusion clamp Complexin alters synaptic transmission and synaptic development at Drosophila glutamatergic neuromuscular junctions
*E. BRIJA1,2, S. K. JETTI1,2, R. W. CHO1,2, J. T. LITTLETON1,2,3;
1The Picower Inst. for Learning and Memory, 2Dept. of Brain and Cognitive Sci., 3Dept. of Biol., MIT, Cambridge, MA
Session P824 Prefrontal Cortex
9:00 AM - 10:00 AM
Presentation P824.05 Layer-specific deactivation of prefrontal cortex as a causal test of predictive coding
*A. J. MAJOR1, A. M. BASTOS2, E. K. MILLER1;
1Picower Inst. for Learning and Memory, MIT, Cambridge, MA; 2Vanderbilt Univ., Nashville, TN
Session P442 Auditory Processing: Neural Coding, Experiment, and Theory
9:30 AM - 10:30 AM
Presentation P442.09 Predictive processing in auditory cortex without consciousness
*Y. XIONG1, J. A. DONOGHUE2, M. K. MAHNKE3, M. LUNDQVIST5, E. N. BROWN4, E. K. MILLER6, A. BASTOS1;
1Dept. of Psychology, Vanderbilt Univ., Nashville, TN; 2Brain and Cognitive Sci., 3PILM, 4MIT, Cambridge, MA; 5Picower Inst. for Learning and Memory, Massachussetts Inst. of Technol., Cambridge, MA; 6Picower Inst. Learning Memory, Massachusetts Inst. Technol., Cambridge, MA
Session P807 Working Memory: Circuits
9:45 AM - 10:45 AM
Presentation P807.06 Dynamic stability underlies cortical computations during working memory
L. KOZACHKOV1, M. LUNDQVIST1,4, J.-J. SLOTINE2,3, *E. K. MILLER1;
1Picower Inst. Learning Memory, 2Dept. of Mechanical Engin., 3Dept. of Brain and Cognitive Sci., MIT, Cambridge, MA; 4Dept. of Psychology, Stockholm Univ., Stockholm, Sweden
Session P131 Signal Propagation in Neural Networks
10:30 AM - 11:30 AM
Presentation P131.02 Propofol anesthesia changes dynamic stability in cortex
*L. KOZACHKOV1, A. EISEN1, A. BASTOS1,2, J. A. DONOGHUE1, M. K. MAHNKE1, S. L. BRINCAT1, E. N. BROWN1,3, E. K. MILLER1;
1Picower Inst. Learning Memory, MIT, Cambridge, MA; 2Dept. of Psychology and Vanderbilt Brain Inst., Vanderbilt Univ., Nashville, TN; 3The Dept. of Anesthesia, Critical Care and Pain Med., Massachusetts Gen. Hospital/Harvard Med. Sch., Boston, MA
Wednesday, Nov. 10, 2021
Session P026 Invertebrate Synapses
1:30 PM - 2:30 PM
Presentation P026.02 Establishing the cohort of early active zone proteins and their role in synaptic strength and maturation at the Drosophila neuromuscular junction
*E. J. GUSS, P. PUJOLS VÁZQUEZ, Y. AKBERGENOVA, J. LITTLETON;
Dept. of Biol. and Dept. of Brain and Cognitive Sci., MIT, Cambridge, MA
Session P055 Fragile X: Cellular Mechanisms
2:30 PM - 3:30 PM
Presentation P055.06 Protein synthesis-dependent hyperexcitability of Fmr1-KO visual cortex layer 5 pyramidal cells offers path to identify novel therapeutic targets for the treatment of fragile X syndrome
*M. J. HEINRICH, D. C. STOPPEL, F.-J. WENG, P. K. MCCAMPHILL, R. K. SENTER, M. F. BEAR;
The Picower Inst. for Learning & Memory, MIT, Cambridge, MA
2:30 PM - 3:30 PM
Presentation P055.07 Mglur5 negative modulators for Fragile X: resistance and persistence
*A. J. HEYNEN, D. C. STOPPEL, P. K. MCCAMPHILL, R. K. SENTER, M. F. BEAR;
The Picower Inst. for Learning & Memory, Cambridge, MA
Session P929 Optical Methodology: Development
3:30 PM - 4:30 PM
Presentation P929.09 A coded exposure camera to enhance the speed and SNR of GEVI imaging
*J. ZHANG1, J. P. NEWMAN1, G. BROWN4, C. LINGHU2, P. CHIN4, E. S. BOYDEN2, M. A. WILSON3;
1Dept. of Brain and Cognitive Sci., 2Media Lab., 3Picower Inst. Learn/Memory, MIT, Cambridge, MA; 4Computer Sci., Boston Univ., Boston, MA
Thursday, Nov. 11, 2021
Session P136 Oscillations and Synchrony: LFP Studies I
8:30 AM - 9:30 AM
Presentation P136.07 Traveling waves in the prefrontal cortex during working memory
*S. BHATTACHARYA, S. L. BRINCAT, M. LUNDQVIST, E. K. MILLER;
MIT, Cambridge, MA
Session P780 Modeling and Behavior V
8:30 AM - 9:30 AM
Presentation P780.11 Shifts in learning strategies underlie rodent behavior during dynamic foraging
*N. M. LE1, M. YILDIRIM2, H. SUGIHARA2, Y. WANG1, M. SUR1;
1Brain and Cognitive Sci., 2Picower Inst. for Learning and Memory, MIT, Cambridge, MA
Session P875 Cognitive Planning
8:45 AM - 9:45 AM
Presentation P875.08 A ubiquitous laminar motif of local field potential power across cortical areas, individual subjects and studies
*A. BASTOS1, D. MENDOZA-HALLIDAY2, N. LEE2, M. LICHTENFELD1, A. J. MAJOR2, R. DESIMONE3, E. K. MILLER4;
1Vanderbilt Univ., Nashville, TN; 2MIT, Cambridge, MA; 3MIT, McGovern Inst. Brain Res., Cambridge, MA; 4Picower Inst. Learning Memory, Massachusetts Inst. Technol., Cambridge, MA
Session P100 Presynaptic Organization
9:00 AM - 10:00 AM
Presentation P100.02 Characterization of Molecular Mechanisms that Contribute to Functional Synaptic Diversity Between Tonic and Phasic Motoneurons
*S. K. JETTI1, A. B. CRANE1, Y. AKBERGENOVA1, C. A. WHITTAKER2, N. A. APONTE-SANTIAGO1, *J. T. LITTLETON1;
1Dept. of Brain and Cognitive Sciences, The Picower Inst. for Learning & Memory, 2David H. Koch Inst. for Integrative Cancer Res., MIT, Cambridge, MA
Session P859 Timing and Temporal Processing III
9:15 AM - 10:15 AM
Presentation P859.10 Wireless EEG recordings in freely behaving marmosets reveal potential neuronal correlates of temporal expectation.
*T. DRAGOI1, H. SUGIHARA1, J. SHARMA1, G. FENG2, R. DESIMONE2, M. SUR1;
1Picower Inst. for Learning and Memory, 2McGovern Inst. for Brain Res., MIT, Cambridge, MA
Session P477 Visual Plasticity in Humans and Disease Models
10:00 AM - 11:00 AM
Presentation P477.09 Correction of amblyopia in cats and mice after the critical period
*M.-F. FONG1,2, K. R. DUFFY3, M. P. LEET1, C. T. CANDLER1,4, J. U. DEERE5,1,6, L. MARTIN1,7, J. S. YAO1,8, N. T. LIANG1, K. LIU1, M. F. BEAR1;
1MIT, Cambridge, MA; 2Georgia Tech. and Emory Univ., Atlanta, GA; 3Dalhousie Univ., Halifax, NS, Canada; 4Arizona State Univ., Tempe, AZ; 5Wellesley Col., Wellesley, MA; 6Rockefeller Univ., New York, NY; 7Brandeis Univ., Waltham, MA; 8Johns Hopkins Univ., Baltimore, MD
10:00 AM - 11:00 AM
Presentation P477.07 Using the visual cliff assay to detect and study recovery from amblyopia in mice
*H. DE JESÚS-CORTÉS1, D. A. BOWEN2,1, A. MORELLO-MEGIAS1, S. I. TORRES-BIGIO1, P. A. ALICEA-ROMÁN1, A. M. ALEJANDRO-SOTO1, F. REILLY-ANDÚJAR1, M. F. BEAR1;
1Picower Inst. for Learning and Memory, Brain and Cognitive Sci., MIT, Cambridge, MA; 2Ophthalmology, Boston Children's Hosp., Boston, MA
Session P867 Place Cells II
10:15 AM - 11:15 AM
Presentation P867.04 Animal-to-animal variability in hippocampal context identification
P. NILCHIAN1, M. A. WILSON2, *H. SANDERS3;
1Florida Intl. Univ., University Park, FL; 2Picower Inst. Learn/Memory, 3MIT, Cambridge, MA
Session P935 Probe Design and Engineering: New Recording Methodologies
10:15 AM - 11:15 AM
Presentation P935.02 Multifunctional fiber-based neurotechnology enables cortical neuromodulation in non-human primates
*I. C. GARWOOD1, A. J. MAJOR2, M.-J. ANTONINI1, J. CORREA3, M. K. MAHNKE2, E. K. MILLER2, E. N. BROWN1, P. ANIKEEVA4;
1HST, 2PILM, 3Brain and Cognitive Sci., 4MSE, MIT, Cambridge, MA