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Study finds ‘volume dial’ for turning neural communication up or down

May 06, 2020

… of neurotransmitters when triggered by an influx of calcium ions. But even with SYT1 disabled, synapses could … SYT7 they didn’t see major differences in anatomy or calcium influx that could explain how SYT7 works to limit …

Fruit fly models of human disease

… caused non-neural “glial” cells to retain too much calcium. By 2019 they found out how that led to seizures. The excess of calcium overactivated a protein called calcineurin. That …

Feast or forage: Study finds circuit that helps a brain decide

November 22, 2021

… To keep constant track of neural activity, as indicated by calcium-triggered flashes of light, the Flavell lab invented … of neurons across the worm’s brain, as indicated by calcium-triggered flashes of light. Ji used the scope to …

Study of synapse strength focuses on ‘active zones’

March 16, 2021

… disability. Video from a 2018 Littleton Lab study shows calcium flux (green) indicating the release of glutamate at …

FLARE

… protein). It works quickly because it is triggered by calcium, which is directly involved in neuronal firing, and a …

Optical Quantal Imaging

… through the innovation of tethering a fluorescent calcium sensor to the postsynaptic membrane across from AZs. …

Whole-brain tracking in moving animals

… (typically indicated by flashes triggered by surges of calcium in the cell), the addition of a second light path …

How synapses change

… 4 (Syt4). When the postsynaptic neuron is very active and calcium ions flow in, Syt4 senses that and signals the …

Special Seminar with Evan Feinberg, PhD, UCSF

… at Harvard University, Evan performed the first two-photon calcium imaging study of the superior colliculus and …

MIT Colloquium on Brain & Cognition with Mark Andermann, PhD

… for studying the neural basis of visual perception using calcium imaging in behaving mice. Dr. Andermann’s lab uses …