December 16, 2019
Human Models of Disease
… the Tsai lab, Joel Blanchard is using iPSCs to model the blood-brain barrier, which stringently filters what comes into and goes out of the brain through the blood stream, so he can see how APOE variants affect that. … may differ in Alzheimer’s. A stem-cell based model of the blood brain barrier with the APOE4 Alzheimer's risk gene …