… mice raised in the dark or with MD. A protein called IGF1 stood out. Artificially adding it prevented ODP. As they studied IGF1 more they realized that it promoted synaptic maturation … syndrome, and that giving Rett model mice doses of human IGF1 could help correct problems caused by the mutation not …
… in a synapse-enhancing pathway with a protein called IGF1. Lacking MeCP2 is a cause of the neurodevelopmental … cortex. When they gave MeCP2 knock-out mice injections of IGF1, they restored plasticity to normal levels, opening up a …