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… presenting new insights into how cortical circuits and cells represent sensory information and use it to guide … which appear especially prevalent in neural progenitor cells, occur genomewide and result in substantial differences … Yuan-Ta Lin showed how minibrains grown from trisomy stem cells vs. disomy ones have smaller diameters after 30 …

… the unique patterns of gene expression among different cells in the brain . She has also achieved the first ever … screen in a mammalian brain to discover which genes help cells fight back against the toxic protein that causes … from JPB , Heiman has been using TRAP to determine which cells antipsychotic drugs such as clozapine affect to help …

… , Mount Sinai, "Investigating Mechanisms of Aging with Stem Cells" 1:25-1:45pm: Choi lab Postdoctoral Associate, Jeongtae …

… her lab is investigating Down syndrome by using induced stem cells from patients to grow new “minibrain” organoids. In the …

… our  in vitro  systems are built from induced pluripotent stem cells (iPSC) derived from patients harboring a specific risk … into different brain cell types, and isogenic control cells that share the exact genetic background and differ only …

… how a genetic aberration undermines the function of brain cells and circuits . Learning how things go wrong puts within … survive the disease. The gene, as it turns out, may help cells dispose of protein a ggregates (such as mutant … vs. the more common APOE3 version. In 2018, they used stem cells derived from patients’ skin cells to create …

… waves reactivated sluggish microglia, the brain’s immune cells. The microglia became larger and started scavenging … Restoring gamma waves also appeared to help keep brain cells from dying—preventing brain shrinkage. Moreover, the … memory, discovered how to identify the specific brain cells that encode a particular memory. He also developed a …