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… professor of neuroscience in the Department of Brain and Cognitive Sciences, an affiliate member of The Picower …

… since 1994. These samples included 146 people with no cognitive impairment, 102 with mild cognitive impairment, and 144 diagnosed with … also start to group genes into regulatory circuits that control specific cell functions such as synaptic …

… in The Picower Institute and MIT’s Department of Brain and Cognitive Sciences (BCS). Notably, the authors wrote in eLife … of the protein Gat3. The left image of an experimental control shows the mouse cortex when the protein was not …

… in the brain, but elsewhere. One of their key assays was control mice. The findings have led to clinical trials of … They also found that as information moved from sensory to cognitive regions, the dimensionality of the neural activity …

… a rate code into a temporal code Top-Down Versus Bottom-Up Control of Attention in the Prefrontal and Posterior Parietal … memory-guided visual search The prefrontal cortex and cognitive control Induction of visual orientation modules in auditory …

… Our cognitive abilities come down to how well the connections, or … has been linked to causing intellectual disability. Our cognitive abilities come down to how well the connections, or … two proteins are not merely interchangeable. Compared to control neurons with normal PSD-95 or cells in which PSD-95 …

… cascade effect that ultimately leads to neuronal death and cognitive dysfunction. However, despite evidence of a link … to target the peptide have so far failed to reverse this cognitive decline. Now, in a review paper published in the … trials fail because patients don’t show improvement in cognitive function,” Tsai says. “So there is a disconnection …

… that promotes DNA repair can help to reverse age-related cognitive decline in mice. epigenetics neurodegeneration … DNA damage to genes involved in memory and other cognitive functions. This enzyme is often diminished in both … proteins around which DNA is spooled. These modifications control gene expression by blocking genes in certain …

… different cell types. They each connect to muscles to help control motion in a fly. His lab’s guiding question was why … people who remain cognitively resilient to those with cognitive impairment, a key difference was the relative … help explain the divergence between healthy aging and cognitive decline, and highlight cell-type-specific molecular …