… that they could reverse this damage and improve cognitive function with a drug that activates HDAC1. The study suggests … members of the HDAC family of enzymes, and their primary function is to modify histones — proteins around which DNA is … of damage encode ion channels, which are critical for the function of synapses. Targeting neurodegeneration Several …
… the Broad Institute. Tissue Processing Genetic Engineering Synapse Mapping Neural Circuits Brain Imaging CLARITY MAP … We are applying these technologies for studying brain function and dysfunction using animal models, human clinical …