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Immune & Inflamed

March 01, 2023

… to be more prominent and consequential in Alzheimer’s and Huntington’s disease respectively. Above: A cartoon depicts … the immune system attacking the self.” Happening in Huntington’s In her Huntington’s disease research, Heiman has found evidence of …

A neuron’s neighbors

March 14, 2025

… become compromised in the neurodegenerative disorders Huntington’s disease, frontotemporal dementia, and ALS. And … all of these diseases, Alzheimer’s, Parkinson’s, ALS, and Huntington’s, vascular dysfunction has been noted, so could … Heiman studies neurodegenerative diseases including Huntington’s disease and for years she and her lab had been …

Symposium highlights numerous leads to combat neurodegeneration

September 24, 2020

… potential advances against Alzheimer’s, Parkinson’s, Huntington’s and other diseases neurodegeneration 40Hz … brain diseases such as Alzheimer’s disease, ALS, Huntington’s disease and Parkinson’s disease, but in essence … treat spinal muscular atrophy and is now being tested for Huntington’s disease and ALS. He added that in some of his …

Colloquium with Marcy MacDonald, PhD, Massachusetts General Hospital, Harvard Medical School

… United States http://whereis.mit.edu/?go=46 Colloquium Huntington's Disease Public Event Huntington’s disease, a dominantly inherited … in a large HEAT-repeat protein (huntingtin). Deep Huntington’s disease natural history studies, such as PHAROS, …

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

March 22, 2024

… in neurodegenerative conditions, Heiman said. For example, Huntington’s disease is caused by a well-known mutation in … of human brain vasculature and its changes in Huntington’s and Alzheimer’s disease by Heiman, Kellis, and … revealed many shared biological pathways across ALS, FTLD, Huntington’s, Alzheimer’s, vascular dementia, Lewy body …

'Cellf' Expression

December 20, 2023

… system biology and diseases such as Alzheimer’s and Huntington’s When Biology Assistant Professor Sara Prescott … to use the technique to characterize how cells respond to Huntington’s disease. The findings included that many … in the vascular cells of people with and without Huntington’s disease. They found that an altered innate …

Genome-wide genetic screening in the mammalian brain

… striatum of the mouse brain, a brain region implicated in Huntington’s disease, Parkinson’s disease, and various … team applied this screen in two different mouse models of Huntington’s disease (in which the huntingtin protein forms … clumps) and compared the results from the screen of the Huntington’s model mice to normal mice. When the shRNA or …

From Brazil to Fenway Park, researcher strives to save lives with science

September 10, 2021

… September 10, 2021 Picower People As a researcher studying Huntington’s disease, and as a science communicator working … Covid-19, Izabella Pena is focused on keeping people safe. Huntington's Disease DEIJ As a researcher studying Huntington’s disease, and as a science communicator working …

Aging Brain Initiative symposium showcases ‘cutting edge’ research across MIT

November 01, 2023

… region called the striatum. She gave an example of work on Huntington’s disease, a neurodegenerative disease of aging. … for analyzing the “multi-omics” of diseases including ALS, Huntington’s and Alzheimer’s. From the podium to the posters, …