Disorders

Picower Institute scientists investigate the pathophysiological mechanisms underlying complex disorders of the brain that affect emotion and cognition. To learn more about research in these or other areas, select them under "Research Topics" and you'll find relevant Picower people, discoveries and events.

Memory and its meaning

October 7, 2019
News Feature
25 Years of Picower Institute research

Study pinpoints Alzheimer’s plaque emergence early and deep in the brain

October 4, 2019
Research findings
Amyloid emerges early in deep regions such as the mammillary body and marches outward along specific circuits

MIT sets out to model Alzheimer’s disease complexity on a chip

October 3, 2019
New Research
Integrating patient-derived brain cell types with vasculature, computer models will yield powerful research platform

Speeding up drug discovery for brain diseases

July 31, 2019
Research Findings
Whitehead, Picower team finds drugs that activate a key brain gene; initial tests show promise for rare, untreatable neurodevelopmental disorder

Neuroscientists look to the body to better understand the brain

July 1, 2019
News Feature
Studies yield new insights into behavior, development, anesthesia

Why visual stimulation may work against Alzheimer’s

May 7, 2019
Research Findings
New findings help explain the surprising discovery that exposure to flickering light reduces amyloid plaques in mice

A comprehensive map of how Alzheimer’s affects the brain

May 1, 2019
Research findings
Analysis of genes altered by the disease could provide targets for new treatments

Alana gift to MIT launches Down syndrome research center, technology program for disabilities

March 20, 2019
New Research Center
Foundation’s $28.6 million gift will fund science, innovation, education to advance understanding, ability, inclusion.

Brain wave stimulation may improve Alzheimer’s symptoms

March 14, 2019
Research findings
Noninvasive treatment can improve Alzheimer’s symptoms such as memory loss and amyloid plaque buildup in mice.

Blending big data and benchtop biology, Tsai and Kellis labs tackle brain diseases

February 21, 2019
News Feature
With new grants, collaboration will take on new questions of dementia

New faculty member studies immune system effect on the brain

February 20, 2019
Picower People
Gloria Choi's research has connected maternal infection with neurodevelopmental disorders

Tsai earns Hans Wigzell Research Foundation Science Prize

January 23, 2019
Picower People
Award recognizes Alzheimer's disease research