Cognition and Motivation

Picower Institute scientists study behaviors and cognitive processes including learning, memory, emotion, reasoning and consciousness. To learn more about these or other areas of inquiry, select them under Research Topics and you'll find relevant Picower people, discoveries and events.

Statistical model defines ketamine anesthesia’s effects on the brain

September 3, 2021
Research Findings
Neuroscientists at MIT and Massachusetts General Hospital have developed a statistical framework that rigorously describes the brain state changes that patients experience under ketamine-induced anesthesia.

Brain’s ‘memory center’ needed to recognize image sequences but not single sights

July 26, 2021
Research Findings
The visual cortex stores and remembers individual images, but when they are grouped into a sequence, mice can’t recognize that without guidance from the hippocampus

Grant to help scientists test whether brain region is a key locus of learning

July 23, 2021
New Research
Long thought of as a generic alarm system, the locus coeruleus may actually be a sophisticated regulator of learning and behavior, an MIT team posits

Memory making involves extensive DNA breaking

July 6, 2021
Research Findings
To quickly express genes needed for learning and memory, brain cells snap both strands of DNA in many more places and cell types than previously realized, a new study shows

As novel sights become familiar, different brain rhythms, neurons take over

June 8, 2021
Research Findings
As ‘visual recognition memory’ emerges in visual cortex, one circuit of inhibitory neurons supplants another and slower neural oscillations prevail

New algorithms show accuracy, reliability in gauging unconsciousness under general anesthesia

May 6, 2021
Research Findings
Machine learning software advances could help anesthesiologists optimize drug dose

Anesthesia doesn't simply turn off the brain, it changes its rhythms

April 27, 2021
Research Findings
Simultaneous measurement of neural rhythms and spikes across five brain areas in animals reveals how propofol induces unconsciousness

Mice naturally engage in physical distancing, study finds

March 31, 2021
Research Findings
MIT neuroscientists have identified a brain circuit that stops mice from mating with others that appear to be sick

Bigger than a Building

March 10, 2021
Picower People
Our first ever census of alumni and former research staff shows a thriving community that spans the globe and many different roles

Neural networks need more than neurons, new project posits

March 4, 2021
New Research
With a new grant from the U.S. Army, a team of scientists will seek to enhance artificial intelligence by integrating brain cells called astrocytes

Steven Flavell earns Sloan Research Fellowship

February 16, 2021
Picower People
Award supports fundamental research on how the brain generates internal states that guide animal behavior

As you look around, mental images bounce between right and left brain

February 8, 2021
Research Findings
New study explains how the brain helps us remember what we’ve seen, even as it shifts around in our visual system