Cognition and Motivation

Picower Institute scientists study behaviors and cognitive processes including learning, memory, emotion, reasoning and consciousness. To learn more about these or other areas of inquiry, select them under Research Topics and you'll find relevant Picower people, discoveries and events.

Mind to molecules: Does brain’s electrical encoding of information ‘tune’ sub-cellular structure?

May 22, 2023
Research Findings
Brain waves carry information. A new “Cytoelectric Coupling” hypothesis posits that fluctuating electric fields optimize brain network efficiency and stability by shaping the brain’s molecular infrastructure.

From molecular to whole-brain scale in a simple animal, study reveals serotonin’s effects

May 15, 2023
Research Findings
With full genetic control and visibility into neural activity and behavior, MIT scientists map out chemical’s role in behavior

A new peptide may hold potential as an Alzheimer’s treatment

April 12, 2023
Research Findings
The peptide blocks a hyperactive brain enzyme that contributes to the neurodegeneration seen in Alzheimer’s and other diseases.

Fluid flow in the brain can be manipulated by sensory stimulation

April 10, 2023
Research Findings
Blood flow induced by visual stimulation drives the flow of cerebrospinal fluid

Studying consciousness without affecting it

April 6, 2023
Research Findings
A new study tests an alternative to external stimulation for measuring when subjects lose and regain responsiveness during sedation and anesthesia.

‘Spatial Computing’ enables flexible working memory

March 15, 2023
Research Findings
Brain applies rhythms to physical patches of the cortex to selectively control just the right neurons at the right times to do the right things.

Astrocyte cells critical for learning skilled movements

March 10, 2023
Research Findings
When astrocyte function is disrupted, neurons in the brain’s motor cortex struggle to execute and refine motion, a new study in mice shows.

Holding information in mind may mean storing it among synapses

December 29, 2022
Research Findings
Comparing models of working memory with real-world data, MIT researchers found that information resides not in persistent neural activity, but in the pattern of their connections

Small studies of 40Hz sensory stimulation confirm safety, suggest Alzheimer’s benefits

December 1, 2022
Research Findings
MIT researchers report early stage clinical study results of tests with non-invasive 40Hz light and sound treatment

Research offers insights into mechanisms underlying bipolar mania, sleep homeostasis

November 23, 2022
Recent Events
At a press conference at Society for Neuroscience Annual Meeting, young Picower scientist Takato Honda presented findings of key neurons involved in the neuropsychiatric disorder and sleep homeostasis

Analyzing brain waves demystifies general anesthesia

November 14, 2022
Recent Events
At Neuroscience 2022, Emery N. Brown relayed how statistical analysis of brain rhythms in patients and animals under anesthetics has revealed important information about how the drugs work.

Are covid ‘comas’ signs of a protective hibernation state?

November 7, 2022
Research Findings
Scientists hypothesize that, as in a hibernating turtle, the brain under sedation and deprived of oxygen may assume a protective state