Against a dark blue background we see two sine waves shifted out of phase with eachother
May 12, 2025
Different anesthetics, same result: unconsciousness by shifting brainwave phase
Neurons glow green against a black background in a section of a mouse brain. A few red specks can be seen. An inset magnifies one of these cells that has red and green staining.
April 28, 2025
Dopamine signals when a fear can be forgotten
A 2 by 2 array of panels that each show a hairpin-like shape of blue stained cells. The left column is laberled "Ambient light/sound." The right column is labeled "40Hz Stimulation." The panels in the 40Hz column show more yellow arrows pointing white blotches than the panels in the ambient column.
April 24, 2025
In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity
Emery Brown sits behind his desk in his MIT office. A teddy bear rests nestled among some books on a shelf behind him, just over his right shoulder.
April 21, 2025
In kids, EEG monitoring of consciousness safely reduces anesthetic use
In a grayscale image a wiggly worm is seen in a vertical orientation above a lumpy background of bacteria
April 8, 2025
A simple animal’s response to sickness highlights the nervous system’s surprising degrees of flexibility

'Risky' Research

December 20, 2021
Research Feature
How bold new neuroscience research projects get off the ground

Research finds potential mechanism linking autism, intestinal inflammation

December 7, 2021
Research Findings
Moms infected during pregnancy who produce elevated levels of the cytokine IL-17a may have microbiome alterations that prime offspring for aberrant immune responses later in life, mouse study suggests

Study reveals a protein’s key contribution to heterogeneity of neurons

November 29, 2021
Research Findings
Tomosyn’s tight regulation of neurotransmitter release distinguishes functions of two neuron classes at the fly neuromuscular junction

Feast or forage: Study finds circuit that helps a brain decide

November 22, 2021
Research Findings
By integrating multiple sensory inputs, a loop of mutual inhibition among a small set of neurons allows worms to switch between long-lasting behavioral states

Young Picower scientists present projects at ‘SfN’

November 12, 2021
Picower People
Picower scientists shared research on brain waves, new technologies, brain plasticity and psychiatric illness and, of course, learning and memory.

Study links gene to cognitive resilience in the elderly

November 3, 2021
Research Findings
The findings may help explain why some people who lead enriching lives are less prone to Alzheimer’s and age-related dementia

Symposium spotlights crucial roles of dendrites

October 18, 2021
Recent Events
Scholars from around the world gathered online to share new research on how intricately structured neural processes enable plasticity of circuit connections and help integrate incoming information to enable brain function

NIH award funds innovative investigation of neurodegenerative motor diseases

October 5, 2021
New Research
Large-scale, integrated application of advanced computational, biological techniques aims to discover mechanisms underlying ALS and frontotemporal lobar degeneration with motor neuron disease

Study shows fragile X treatment can incur resistance, suggests ways around it

September 29, 2021
Research Findings
While the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise if dosing occurs intermittently and during a developmental critical period

'What Were you Thinking?'

September 20, 2021
Research Feature
How brain circuits integrate many sources of context to flexibly guide behavior

From Brazil to Fenway Park, researcher strives to save lives with science

September 10, 2021
Picower People
As a researcher studying Huntington’s disease, and as a science communicator working tirelessly to keep Portuguese- and Spanish-speaking communities informed about Covid-19, Izabella Pena is focused on keeping people safe.

Behind the scenes, brain circuit ensures vision remains reliable

September 8, 2021
As mice watched movies, scientists watched their brains to see how vision could be represented reliably. The answer is that consistency in representation is governed by a circuit of inhibitory neurons