On March 10 the FDA approved Trofinetide, a drug based on the protein IGF-1, as the first drug available to treat Rett syndrome. The original research showing that IGF-1 could treat Rett syndrome was published by MIT in 2009.

When astrocyte function is disrupted, neurons in the brain’s motor cortex struggle to execute and refine motion, a new study in mice shows.

Neuroscientists are finding that immune system activity within the brain and the body has important impacts on mental health and behavior

Young neuroscientists contributed their perspectives as the MIT Museum works to create a potential ‘Center for Neuroscience & Society’

Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue

First detailed mapping and modeling of thalamus inputs onto visual cortex neurons show brain leverages “wisdom of the crowd” to process sensory information

A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement

Using these engineered proteins, researchers can record histories that reveal when certain genes are activated or how cells respond to a drug.

‘Single-cell profiling’ is helping neuroscientists see how disease affects major brain cell types and identify common, potentially targetable pathways

Comparing models of working memory with real-world data, MIT researchers found that information resides not in persistent neural activity, but in the pattern of their connections

MIT researchers report early stage clinical study results of tests with non-invasive 40Hz light and sound treatment

At a press conference at Society for Neuroscience Annual Meeting, young Picower scientist Takato Honda presented findings of key neurons involved in the neuropsychiatric disorder and sleep homeostasis