A cross section of a mouse brain glows with a magenta hue. Many individual speckles across the whole brain are lit up brighter.
January 14, 2026
How a unique class of neurons may set the table for brain development
A realistic rendering shows a wide field of neurons densely bunched together
December 29, 2025
Biology-based brain model matches animals in learning, enables new discovery
On a black background there is a profile of a head with a light colored line-art brain in the middle. The brain has bright spots in various areas. From front and back, waves made of vertical lines emanate from the head.
December 22, 2025
To flexibly organize thought, the brain makes use of space
A view of the upper right quadrant of a cross section of a mouse brain. An arc of tissue extends from the top left to the bottom right. Along the arc there are stripes of neurons glowing in eithe red or green in distinct layers of the tissue
November 25, 2025
Prefrontal cortex reaches back into the brain to shape how other regions function
A 4 by 2 array of panels shows neurons in a brain section. Green "Myc" labeling indicates the presence of a receptor. Magenta "fos" labeling indicates neural activity. There is more magenta on the bottom row, which is labeled "IL-1B"
November 25, 2025
Too sick to socialize: How the brain and immune system promote staying in bed

For high schoolers, summer starts with extra exposure to biomedical science

June 23, 2022
Picower People
Just before school was out for summer, high school students from Everett and Lawrence toured life sciences research labs at MIT to get information and inspiration

How the brain responds to surprising events

June 1, 2022
Research Findings
Unexpected outcomes trigger release of noradrenaline, which helps the brain focus its attention and learn from the event

NIH award to help Heiman unearth roots of Huntington’s pathology

May 26, 2022
New Research
Research Program Award will fund studies to find early triggers of disease progression

Brown wins share of 2022 Gruber Neuroscience Prize

May 17, 2022
Picower People
Emery N. Brown and three other scientists recognized for advancing statistical, theoretical analyses of neuroscience data

Circuit model may explain how deep brain stimulation treats Parkinson’s disease symptoms

May 16, 2022
Research Findings
Stimulation of subthalamic nucleus interrupts a cycle of runaway beta-frequency rhythms and restores ability of interneurons to regulate rhythms in the brain’s striatum, improving movement, study suggests

Anesthetic drastically diverts the travels of brain waves

April 27, 2022
Research Findings
Under propofol general anesthesia very slow frequency traveling waves transform and dominate, redirecting and disrupting the higher frequency traveling waves associated with conscious function

Circuit that focuses attention brings in wide array of inputs

April 21, 2022
Research Findings
With a comprehensive map of the wiring, researchers can now discern what information flows into the circuit to enable a key brain function

Aging Brain Initiative awards fund 5 new ideas to study, fight neurodegeneration

April 20, 2022
New Research
Competitive seed grants launch yearlong investigations of novel hypotheses about potential causes, biomarkers, treatments of Alzheimer’s and ALS.

A single memory is stored across many connected brain regions

April 11, 2022
Research Findings
Innovative brain-wide mapping study shows that “engrams,” the ensembles of neurons encoding a memory, are widely distributed, including among regions not previously realized

Emery Brown earns AIMBE’s highest honor

March 25, 2022
Picower People
Pierre Galletti Award recognizes contributions to neural signal processing, anesthesiology advances

Neurons are fickle. Electric fields are more reliable for information.

March 14, 2022
Research Findings
A new study suggests that electric fields may represent information held in working memory, allowing the brain to overcome “representational drift,” or the inconsistent participation of individual neurons

The model remodeler

March 14, 2022
Research Feature
A Picower Institute primer on ‘plasticity,’ the brain’s amazing ability to constantly adapt to and learn from experience