a cartoon of a brain with cogs and gears
August 17, 2026
Flexible brain circuits can switch between different tasks
Over a tangle of dark blue neurons, bright orange spots appear along the lengths of some of the axons, highlighting their paths through the tangle
August 13, 2026
Brain circuit keeps tabs on what just happened to aid judgement of what’s happening now
Shanshan Zhang and Rosie Firenze stand before a Massachusetts Life Sciences Center backdrop holding and award certificate
July 29, 2026
With Mass. Women’s Health Award, team will study how Alzheimer’s risk varies with hormone replacement
Emery Brown sits behind his desk in his MIT office. A teddy bear rests nestled among some books on a shelf behind him, just over his right shoulder.
July 20, 2026
MIT names Emery N. Brown an "Institute Professor," its highest faculty honor
A portrait of Susumu Tonegawa in front of a gray background
July 15, 2026
Picower Professor Susumu Tonegawa, renowned molecular biologist and Nobel laureate, dies at 86

A “golden era” to study the brain

October 4, 2022
Picower People
“We can’t think of the brain only as neurons,” says PhD student Mitch Murdock, who explores the cellular basis of Alzheimer’s disease

To the clinic!

October 4, 2022
Research Feature
When fundamental research yields discoveries with medical potential, Picower Institute professors find ways to test whether they’ll help patients.

Providing new pathways for neuroscience research and education

September 29, 2022
Picower People
Payton Dupuis finds new scientific interests and career opportunities through MIT summer research program in biology.

Celebrating 20 years of discovery, Picower Institute looks ahead to continuing impact

September 28, 2022
Recent Events
At an exhibition marking two decades since a transformative gift from The Picower Foundation, current and alumni members described research at the forefront of neuroscience and beyond

With fractured genomes, Alzheimer’s neurons call for help

September 28, 2022
Research Findings
Study indicates that ailing neurons may instigate an inflammatory response from the brain’s microglia immune cells

Simple animal model reveals how environment and state are integrated to control behavior

September 6, 2022
Research Findings
A new study shows how stimuli and states such as smells, stressors and satiety converge in an olfactory neuron to guide food-seeking behavior

How the brain focuses on what’s in mind

September 5, 2022
Research Findings
When holding information in mind, neural activity is more focused when and where there are bursts of gamma frequency rhythms

Microscopy technique reveals hidden nanostructures in cells and tissues

August 29, 2022
Research Findings
Separating densely packed molecules before imaging allows them to become visible for the first time

When Alzheimer’s degrades cells that cross hemispheres, visual memory suffers

August 19, 2022
Research Findings
New research reveals cells that span brain hemispheres to coordinate activity in visual processing centers and shows that Alzheimer’s degrades their structure and therefore their function

At a research forefront, young scholar looks ahead to graduate school, chance to mentor others

August 15, 2022
Picower People
As he works to solve an advanced problem at the intersection of computing and neurobiology, Picower Institute post-baccalaureate scholar Eric Bueno is also thinking of how he could pay his experience forward

When a task adds more steps, this circuit helps you notice

August 5, 2022
Research Findings
By tracking feedback during tasks, the anterior cingulate cortex notices when a new step has become necessary and signals the motor cortex to adjust

How microglia contribute to Alzheimer’s disease

August 4, 2022
Research Findings
A breakdown of lipid metabolism in these brain cells promotes inflammation and interferes with neuron activity, a new study finds