Site Search

… 2025 Research Findngs Cultured from induced pluripotent stem cells, ‘miBrains’ integrate all major brain cell types and … activity, and pathological features. organoids stem cells Alzheimer's dementia …

… tissues to detect the molecular activity of individual cells by using sound. “The major advance here is to enable us … a 3D-mini brain-like tissue generated from human stem cells, and a 0.7 mm thick slice of mouse brain tissue. In …

… In Down syndrome cells, genome-wide disruptions mimic a senescence-like state … correct them in cell cultures. The study published in Cell Stem Cell therefore establishes senescence as a potentially … only by whether they had a third copy of chromosome 21. Stem cells derived from volunteers were cultured to turn into …

… “We found pretty strikingly that when we treated these cells with choline, a lot of the transcriptional defects were … variants into neurons derived from induced pluripotent stem cells. These cells showed many of the same gene … went down. The researchers then used induced pluripotent stem cells to generate 3D tissue organoids made of neurons …

… same neurons regulate the immune system, and can signal to stem cells to promote or suppress tissue repair. These are …

… goes awry in many diseases. airway-to-brain signaling stem cells neural systems As a newly named Pew Scholar in the … such as coughing, and repair responses that marshal stem cells to remodel damaged tissue. But in many diseases, …

… or “mini-brains.” To grow these cultures, a donor’s skin cells are reprogrammed to become induced pluripotent stem cells and those are then biochemically coaxed from that …

… Findings A breakdown of lipid metabolism in these brain cells promotes inflammation and interferes with neuron activity, a new study finds organoids iPSCs stem cells neurodegeneration ApoE lipid metabolism https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(22)00300-9 A breakdown of lipid …