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Symposium highlights numerous leads to combat neurodegeneration

September 24, 2020

… neurons that died during disease, restoring the essential function of producing the neurotransmitter dopamine. Above: … may cause further protein aggregation that affects brain function. One of the proteins whose aberrant behavior is most …

Research highlights immune molecule’s complex role in Huntington’s disease

May 26, 2020

… connection genes neuroimmunology Huntington's Disease synapse function Neuroimmune interactions …

Genes & plasticity in memory

… a full memory when only given incomplete cues (a mental function called pattern completion). Five years later they … transmission in hippocampal circuits to determine their function. The innovative study showed that a long circuit …

Key roles for astrocytes

Mechanisms and therapeutics for Rett Syndrome

… neural plasticity in the mice, promoting improved brain function. In 2014 they complemented those results using doses … another study finding that a critical problem for neural function in MeCP2 deficient mice was that neurons responsible … of factors during development that lead to altered brain function. Scientists tracked the migration of young neurons …

Special Seminar with Emily Osterweil, PhD, The University of Edinburgh

… States https://whereis.mit.edu/?go=46 Special Events Synapse Mapping Neural Circuits Public Event This seminar … how mRNA translation in neurons contributes to brain function, and to identify how disruptions in this process …

Behind the scenes, brain circuit ensures vision remains reliable

September 08, 2021

… fidelity of sensory processing. A potential biophysical function of the SST à PV circuit may be to maximize the …

Study finds that aging neurons accumulate DNA damage

May 18, 2020

… that they could reverse this damage and improve cognitive function with a drug that activates HDAC1. The study suggests … members of the HDAC family of enzymes, and their primary function is to modify histones — proteins around which DNA is … of damage encode ion channels, which are critical for the function of synapses. Targeting neurodegeneration Several …

Innovations giving neuroscientists exciting new ways to gain insights, symposium speakers say

October 25, 2018

… the brain, both to understand its healthy anatomy and function and to better understand disease. The emerging … to turn around and understand how we can control brain function and understand cognition, it really is a golden …

Neural Mechanisms of Memory and Cognition

… 9:40am: Jessica Cardin, “ State-dependent cortical circuit function” 9:40 - 10:15am: Martin Fuhrmann, “ How memories are … 10:15 - 10:50am: Elly Nedivi, “ Visualizing events in synapse formation in vivo ” 10:50 - 11:20am: Break 11:20 - …