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Picower Fellows alumni

… leading to experience dependent changes in synaptic plasticity. Karen Cunningham Brady Weissbourd In the new … with a particular focus to study methods to modify neural plasticity in multiple sclerosis. Kyung-Seok Han Weifeng Xu … his research interests on how astrocytes affect synaptic plasticity in the learning and memory as well as addiction. …

Bear elected member of National Academy of Medicine

October 17, 2022

… change in response to experience, a capability known as “plasticity.” In 2006, for example, Bear and co-authors … normal, or “fellow,” eye resets the threshold for synaptic plasticity, allowing incoming sensory input to strengthen …

MIT Colloquium on Brain & Cognition with Sara Aton, PhD

Mechanisms and therapeutics for Rett Syndrome

… or synapses, to change with experience (a property called “plasticity”), the lab of Mriganka Sur, Newton Professor of … last year. The lab discovered the role of IGF1 in neural plasticity in 2006 when they showed that it critically … left open (a dramatic phenomenon called ocular dominance plasticity). In 2009 they revealed that IGF1 was also …

Multi-color two-photon microscopy

… & Inventions Elly Nedivi ’s studies of synaptic structural plasticity have required her to be able to independently …

Study finds ‘volume dial’ for turning neural communication up or down

May 06, 2020

Nedivi named to new professorship

February 07, 2019

… the cellular mechanisms that underlie activity-dependent plasticity in the developing and adult brain through studies … the proteins they encode. Her work to identify “candidate plasticity genes” has yielded many insights, including …

CPG2

… to change and adapt with experience (a property known as plasticity) can also be sources of vulnerability to disease … called CPG2, encoded by the gene SYNE1, critically enables plasticity during health but significantly increases … postdoc to find genes and molecules that implement neural plasticity. Ever since, her Picower Institute lab has been …

Morgan Sheng

Orthogonal scanning microscope

… & Inventions The brain’s ability to learn comes from “plasticity,” in which neurons constantly edit and remodel the … they make with other neurons to form circuits. To study plasticity, neuroscientists seek to track it at high resolution across whole cells, but plasticity doesn’t wait for slow microscopes to keep pace, …