Site Search

The model remodeler

March 14, 2022

… be working to increase or decrease information flow as a function of behavioral change , ” Littleton said. Built to … of proteins are involved in building and operating e very synapse , both on the “pre-synaptic” (axonal) side and the … the connection. S ome of these proteins contribute to the synapse ’ s structure . Some on the pre-synaptic side …

Study suggests new molecular strategy for treating fragile X syndrome

February 20, 2025

… neurons, called spines, were critical in understanding the function of NMDA receptors in the new study, as well as a … that the dichotomy of ionic effects on synaptic function and non-ionic effects on spine structure might …

‘Rewiring’ cortical circuits

… manifest at the connection between two neurons called a synapse and that most of the synapses neurons form to receive … in this screen were used to restore normal plasticity and function in animal models of brain disorders. In a 2011 … processing a different input strengthened a particular synapse on the neuron. When that happened, the team observed …

Protein has unique effects in neural connections related to information processing

October 09, 2018

New autism research projects represent a broad range of approaches to achieving a shared goal

November 21, 2024

… autistic brain. neuroimmunology Neuroimmune interactions synapse function At a symposium of the Simons Center for the Social … of molecular gates regulating ion exchange at the synapse , which would in turn affect how frequently and …

Plasticity and place: Study shows a key neural mechanism of remembering locations

March 25, 2024

… physiology hippocampus spatial memory inhibitory neurons synapse function https://www.science.org/doi/10.1126/science.adk3863 …

Fruit fly models of human disease

… has been studying the effects of loss of normal Huntingtin function in Drosophila models since 2009, yielding a series … harmfully misaggregates . They’ve found loss of normal function causes defects in the transport of mitochondria and … the transcription of genes that promote maturation of the synapse as they normally would. To set the stage for …