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… has discovered that when the precursors to myelinating cells called oligodendrocyte precursor cells harbor cancerous mutations, the tumors that … in science. Kara McKinley , an assistant professor of stem cell and regenerative biology at Harvard, noted that …

… decided to explore the role of sirtuins in endothelial cells, which line the inside of blood vessels. To do that, … which encodes the major mammalian sirtuin, in endothelial cells of mice. They found that at 6 months of age, these mice … Vittorio Sartorelli, chief of the Laboratory of Muscle Stem Cells and Gene Regulation at the National Institute of …

… of Alzheimer’s disease, which affects many types of cells in the brain including its blood vessels, has proven … and validated such an in vitro BBB from patient-derived stem cells. Moreover, he made versions with the Alzheimer’s risk …

… MIT shows that this gene has widespread effects on brain cells’ ability to metabolize lipids and respond to stress. In studies of human brain cells and yeast cells, the researchers found that the APOE4 … the researchers created human induced pluripotent stem cells that carry either the APOE3 or APOE4 gene in an …

… the harmful inflammatory response of the brain’s immune cells, reducing disease pathology, preserving neurons and … the harmful inflammatory response of the brain’s immune cells, reducing disease pathology, preserving neurons and … of human microglia-like cells cultured from patient stem cells. When they exposed the microglia-like cells to …