… of ApoE, and the increasingly recognized role of lipid metabolism in Alzheimer’s disease. "Unearthing these … DEGs associated with AD are linked to lipid/cholesterol metabolism, to AD genetic risk factors (including ApoE) and …
… Rhythms Neuroimmune interactions myelination ApoE lipid metabolism Neuronal DNA damage 46-4235 617-324-1658 … to expression differences for genes associated with lipid metabolism and storage. In follow-up studies using our …
… which showed that APOE4-induced dysfunction of lipid metabolism in neurons by cellular accumulation of unsaturated … pathway in neuronal cells, thus stabilizing the lipid metabolism and concomitantly restoring normal cell function …
