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Symposium spotlights crucial roles of dendrites

October 18, 2021
… called the thalamus forge synapses with neurons in the cortex to regulate the response to regularly repeated, and … to see it in action across dendrites in a wide area of the cortex. Masanori Murayama of the RIKEN Center for Brain … by overlapping groups of neurons in the retrosplenial cortex, but even become linked at the level of dendrites. She …

Brain waves and cognition

… rhythms, or brain waves, play a central role in how the cortex processes information and gives us volitional control … Brain rhythms sculpt the flow of information across the cortex. Here we see that the peak frequency of beta rhythms … that bursts of top-down beta waves from deep layers of the cortex typically govern when gamma waves can flow in more …

Rhythmic interactions between cortical layers control what we hold in mind

January 15, 2018
… of working memory oscillations working memory prefrontal cortex … synchronizing neurons in distinct layers of the prefrontal cortex (PFC), the area of the brain associated with higher … (blue) and beta (red) combine like jazz rhythms in the cortex. Learn more below Layers of waves To conduct the …

New faculty member studies immune system effect on the brain

February 20, 2019
… neurodevelopmental disorders proprioception cortex Gloria Choi , the newest faculty member of the Picower … influence the development and activity of neurons in the cortex. In the same spirit she learned in Axel’s lab, she has … neural inhibition specifically in the S1DZ region of the cortex. The team showed that by intervening to reduce excess …

Picower scientists shine in Chicago at 'SfN'

October 28, 2019
… the importance of different neural signals recorded in the cortex of experimental animals as they carried out cognitive … of neural rhythms the lab has documented in the prefrontal cortex during working memory appears to be a general feature … up to present a poster showing that the anterior cingulate cortex region of the prefrontal cortex regulates the …

Technologies enable 3D imaging of whole human brain hemispheres at subcellular resolution

June 13, 2024
… constituents (in distinct colors) within the orbitofrontal cortex of a brain donor with Alzheimer’s disease. Exploring … They focused most of their analysis in the orbitofrontal cortex within each hemisphere. One of the many observations … A comparison of what can be seen in the orbitofrontal cortex of control and Alzheimer’s brain samples: Note in …

'What Were you Thinking?'

September 20, 2021
… the more norepinephrine a mouse will send to the motor cortex, which plans movement, before pushing the lever – as … will send a burst of norepinephrine to the prefrontal cortex to note that pleasant surprise. The biggest post-push … wrong: that norepinephrine release to the prefrontal cortex appears to signal that the adverse result must be …

When Alzheimer’s degrades cells that cross hemispheres, visual memory suffers

August 19, 2022
… their structure and therefore their function visual cortex neurodegeneration synapse gamma … work identified neurons that connect the primary visual cortex (V1) of each hemisphere and showed that when the cells … in memory such as the hippocampus or the prefrontal cortex. Curious about how this might differ in Alzheimer’s …
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