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… A new deep learning algorithm trained to optimize doses of propofol to maintain unconsciousness during general … A new deep learning algorithm trained to optimize doses of propofol to maintain unconsciousness during general … for continuously automating dosing of the anesthetic drug propofol. Using an application of deep reinforcement …

… their 20s underwent anesthesia with the commonly used drug propofol. As the dose was methodically raised using computer … predictive of consciousness and unconsciousness under propofol. Then the researchers tested the algorithms in three … EEG recorded from 27 real surgery patients who received propofol for general anesthesia. Even though the algorithms …

… about how the drugs work. anesthesia consciousness propofol ketamine At Neuroscience 2022, Emery N. Brown … hit in the brain,” Brown said. For instance, during propofol anesthesia, which targets inhibitory GABAergic …

… statistical analyses to characterize brain activity under propofol anesthesia, but as the new study makes clear, … major implication is already apparent, Brown said. Whereas propofol causes brain activity to become dominated by very …

… brain state measurements to constantly optimize doses of propofol to maintain a desired level of unconsciousness. In …

… A non-human primate model for closed-loop control of propofol-induced unconsciousness *S. CHAKRAVARTY 1 , J. A. … oscillations: Spatially coherent alpha dynamics during propofol-induced unconsciousness reflect functional … AA43 Testing the mechanisms of cortical fragmentation with propofol induced loss of consciousness and large scale …