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‘Rewiring’ cortical circuits

… between two neurons called a synapse and that most of the synapses neurons form to receive input from others reside on … the fate of the spines on those dendrites that house many synapses. In 2003, for example, the lab showed an important … too. The Sur lab has not only looked at changes among synapses on dendritic spines, but also at the underlying …

The model remodeler

March 14, 2022

… the individual connections between neurons , called synapses ; across groups of synapses on each neuron; and in … completely. She’s found that even in adult animal brains, inhibitory synapses will transiently appear or disappear to … her research has shown that amid monocular deprivation , inhibitory neurons go so far as to pare down their axons to …

Elly Nedivi

… Neuritin CPG2 SYNE1 visual system In vivo cellular imaging inhibitory circuits Bipolar Disorder 46-3225 617-253-2344 … for labeling and chronic monitoring of excitatory and inhibitory synapses across entire neuronal arbors in the mouse visual …

Mriganka Sur elected to the 2022 class of the AIMBE College of Fellows

February 28, 2022

… Sur for developing technologies to image brain cells, synapses and circuits and applying them innovatively to … research employing two-photon microscopy to reveal how synapses, or the connections between neurons, change in the … cells and investigated roles for neuromodulatory inputs to inhibitory and excitatory neurons in shaping cortical …

'Cellf' Expression

December 20, 2023

Mriganka Sur

… is enabled by circuits comprised of excitatory and inhibitory neurons along with astrocytes, which are wired … by mechanisms of learning and memory. Abnormal wiring of synapses and circuits lies at the core of many brain … His laboratory has discovered core functional rules of inhibitory-excitatory neuronal circuits in the cerebral …

The Developing Brain

July 11, 2018

… In plasticity, the connections between neurons, or synapses, get stronger or weaker. Nedivi wanted to know how. … neural growth. CPG2 expression regulates receptors at the synapses of glutamate-producing neurons. CPG2 also happens to … imaging to allow simultaneous and distinct imaging of inhibitory and excitatory synapses in real time in live mice. …

Fundamental questions find advanced answers, approaches at Fall Symposium

October 18, 2019

… call “plasticity,” begins with the connections, or “synapses,” that neurons form with each other. In her talk … happen by individually labeling different types of synapses under the microscope and tracking how they come and … or cemented, and how cells appear to fleetingly form inhibitory synapses next to permanent excitatory ones perhaps …

Dozens from Picower present research at SfN

November 13, 2018

… monitor and study the frequent assembly and removal of inhibitory neural connections, or synapses, in live animals, which could help explain how … the poster wall from Boivin’s poster on rapid imaging of synapses was that of Littleton lab graduate student Elizabeth …

Mechanisms and therapeutics for Rett Syndrome

… the proteins crucial for allowing neural connections, or synapses, to change with experience (a property called … for computations received too little excitatory and inhibitory drive from others, a circumstance they were able …