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How a mutation in microglia elevates Alzheimer’s risk

November 16, 2023
… green staining highlights human microglia implanted in the hippocampus region of the brain of a mouse. The study is not … mice in a memory-focused region of the brain called the hippocampus. The scientists then stained that region to … the mutated microglia were implanted. Green staining in hippocampus tissue indicates levels of a protein associated …

Neuroscientists find memory cells that help us interpret new situations

April 06, 2020
… are activated when a new, similar event takes place hippocampus CA1 spatial memory … overall experience. These chunks of memory, stored in the hippocampus, are activated whenever a similar type of … It is well-established that certain cells in the brain’s hippocampus are specialized to store memories of specific …

Neuroscientists identify brain circuit necessary for memory formation

April 06, 2017
… challenge standard model of memory consolidation. engram hippocampus prefrontal cortex amygdala … that memories are actually formed simultaneously in the hippocampus and the long-term storage location in the brain’s … then known only as Patient H.M., revealed that the hippocampus is essential for forming new long-term memories. …

Like a treasure map, brain region emphasizes reward location

June 01, 2020
… with a special emphasis on where the reward lies hippocampus spatial memory … activity of hundreds of neurons in the LS and the hippocampus, a region known for encoding many forms of memory … proportion of its cells to encoding location than does the hippocampus, a much larger proportion of those cells respond …

Study finds hub linking movement and motivation in the brain

September 19, 2019
… movement, reward information to help direct behavior hippocampus … Neuroscientists have traced its connections to the hippocampus, a crucial center for encoding spatial memories … the LS directly tracks movement or communicated with the hippocampus, for instance by synchronizing to certain neural …

Plasticity and place: Study shows a key neural mechanism of remembering locations

March 25, 2024
… is required. epilepsy all-optical physiology hippocampus spatial memory inhibitory neurons synapse … labeled and observed two specific kinds of cells in the hippocampus region of the brain, which forms memories of … input via endocannabinoid-mediated DSI. In the mouse hippocampus, scientists engineered inhibitory neurons to …

Time and events in memory

… entorhinal cortex (MEC) plays in infusing memory in the hippocampus with information about timing. In 2011 the lab … a circuit connecting cells in layer 3 of the MEC with the hippocampus. Mice in whom the connection was disrupted, for … cells” in layer 2 of MEC connect into the CA1 area of the hippocampus to control the activity of the connections from …
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