… from the M2 region of the cortex to regions in the brainstem, which actually control the legs, would be … signals down two separate paths that re-converge in the brainstem. Why? Because the difference made by those two … nucleus (STN). The STN certainly then needed to signal the brainstem—specifically the pedunculopontine nucleus (PPN) in …
… work. Opioids combat nociception in the spinal cord and brainstem by binding to opioid receptors, while decreasing … involving the neurotransmitter acetylcholine between the brainstem, the thalamus, and cortex. By contrast, ketamine …