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… in HD, by sequencing RNA in thousands of individual cells in each mouse line. When they looked at the differences … the Hereditary Disease Foundation. 42 25 9 Small Image in Place of Hero On List on Aging Brain Initiative Page On List …

… of brain tissue grown from human induced pluripotent stem cells.   “We have developed a 3D model of human myelination … aging and Alzheimer’s disease influence myelinating cells and neuronal health.” Using the cultures, he’ll be able … impairments later in life,” he said. 2 8 33 Small Image in Place of Hero On List on Aging Brain Initiative Page On List …

… from Harvard University   45 27 20 31 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …

… lab full-time. In the course of the disease, brain cells die amid runaway aggregation of mutant huntingtin … increasingly they have focused on two components within cells: the lysosomes and the mitochondria. In her research, … working to save lives through science. 42 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …

… same task, the participation and activity of individual cells varies (a phenomenon called “representational drift”). … not only from neurons involved in the task but also from cells that were working on unrelated things. So, to isolate … for the research. 44 28 220 16 22 15 Small Image in Place of Hero On List on Aging Brain Initiative Page Off List …

… observed in real brains at work. The idea that brain cells maintain memories by being always “on” may be simpler, … Grants funded the research. 44 22 15 20 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …

… (NE), the LC’s tiny population of surprisingly diverse cells may represent an important regulator of learning from … suggested to be a heterogeneous population of NE-releasing cells, potentially exhibiting both spatial and temporal … learning and cognition. 46 20 13 15 14 5 24 Small Image in Place of Hero On List on Aging Brain Initiative Page Off List …

… withstand rigorous sterilization procedures and to stay in place even in an active animal. And it integrates directly … the effects of activating or inhibiting specific brain cells. Story by  Jennifer Michalowski, courtesy of the … McGovern Institute 44 39 22 220 16 32 279 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …

… encoded voltage indicators” (GEVIs), that make cells glow as their voltage changes in real-time. But as … many pixels are really looking at essentially the same place on the scale of a whole neuron, Wilson said. … support for the research. 49 147 31 Small Image in Place of Hero Off List on Aging Brain Initiative Page Off …