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… neuroscientists at The Picower Institute for Learning and Memory identifies a well-connected brain region as a crucial … to the hippocampus, a crucial center for encoding spatial memories and associating them with context, and to … to certain neural rhythms, about movement and the spatial context of reward. “The hippocampus is one of the …

… and psychiatric illness and, of course, learning and memory. Picower scientists shared research on brain waves, … of sleep, more neurons become involved in representing spatial contexts, fine tuning mental maps of places. Networks … degree to which their brain “remaps” representation of a spatial context when it changes. Wilson lab postdoc Wei Guo, …

… is required. epilepsy all-optical physiology hippocampus spatial memory inhibitory neurons synapse function … plasticity,” in tissue slices rather than during actual spatial navigation behavior, said co-lead author Linlin Fan , …

… has pinpointed exact brain circuits that associate the memory of an experience with a feeling about it. When his lab … could be manipulated to change a negative feeling about a memory into a positive one, messages from people with anxiety … ensemble, or “engram,” of cells that encode a specific memory. Upon pinpointing engram cells, the scientists could …

… a member of MIT’s Picower Institute for Learning and Memory, and one of the senior authors of the new study. … disorders, including disorders of perception, attention, memory, and motor control. In an orchestra, one instrument … has previously put forth, which proposes that the brain’s spatial organization helps it to incorporate new information, …

… , the director of MIT’s Picower Institute for Learning and Memory and the senior author of the study. The researchers … in the mice, which performed much better on tests of spatial memory than untreated mice did. The treatment also produced beneficial effects on spatial memory in older, healthy mice. Chinnakkaruppan …

… the maze in its sleep – a key process in consolidating its memory. In the new study, several of the scientists involved … in open space. The ability to so robustly track the rat’s spatial representations in real-time opens the door to a … of place have helped to show that animals replay their spatial experiences during sleep and have allowed researchers …

… Professor in The Picower Institute for Learning and Memory at MIT, who co-authored the paper in Progress in … how higher-level cognitive functions such as working memory can rapidly, flexibly and yet reliably emerge from the … neurons for flexible cognition, a concept called “ Spatial Computing .” Other recent work from the lab has shown …

… that helps the brain record memories of new locations. spatial memory circuits hippocampus … between the LC and CA3 are necessary for long-term spatial memories to form in CA3. “The selectivity of …

… or haven’t changed enough to be a new context hippocampus spatial memory bayesian modelling … hippocampus, the brain creates a new map for every unique spatial context – for instance, a different room or maze. But …