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… by choline supplements neurodegeneration Cellular and Molecular ApoE lipid metabolism … performed a systematic genetic screen to determine the molecular basis of the defects seen in APOE4 cells. This …

… DNA and then, when it apparently fails, sending out via molecular signals to microglia, which responded by taking on … transcription in neurons by interfering with a key molecular cog in that machinery called p65. That step …

… memory cells, promise an opportunity to identify effective molecular targets for treatment of emotional disorders such … the RIKEN Brain Science Institute. “The identification of molecular markers for the different amygdala cell populations …

… of more than 200 peer-reviewed publications focused on the molecular cellular biology of synapses and synaptic … mechanisms of neurodegenerative diseases. Sheng’s molecular studies of the structure and function of synapses … and coworkers made important discoveries regarding the molecular mechanisms of synapse weakening and loss, the …

… when they could not before. “eMAP preserves the fine-scale molecular architecture of synapses and can facilitate … that inhibitory synapses are not homogenous in their molecular content and show that eMAP is a powerful tool for …

… plasticity plasticity synaptic plasticity Cellular and Molecular … for Learning and Memory have identified a specific molecular mechanism that appears to undermine the ability of …

… Rett syndrome therapeutic? We decided to study the molecular basis of ocular dominance plasticity using a … plasticity we could intervene to potentially offset the molecular and synaptic deficits and treat the disorder. This …

… level, using a multidisciplinary approach that combines molecular biology and electrophysiology with computational … Systems-level analyses In addition to investigating the molecular and cellular processes underlying Alzheimer’s … provide powerful model systems for unraveling some of the molecular and cellular mechanisms underlying Alzheimer’s …

… so the mechanisms of action are known,” said Tang. “Such molecular insights enable us to learn how the KCC2 gene is … compounds), work in a variety of ways. Some block a molecular pathway, called FLT3, which is found to be …