Site Search

… the harmful inflammatory response of the brain’s immune cells, reducing disease pathology, preserving neurons and … the harmful inflammatory response of the brain’s immune cells, reducing disease pathology, preserving neurons and … of human microglia-like cells cultured from patient stem cells. When they exposed the microglia-like cells to …

… of Alzheimer’s disease, which affects many types of cells in the brain including its blood vessels, has proven … and validated such an in vitro BBB from patient-derived stem cells. Moreover, he made versions with the Alzheimer’s risk …

… MIT shows that this gene has widespread effects on brain cells’ ability to metabolize lipids and respond to stress. In studies of human brain cells and yeast cells, the researchers found that the APOE4 … the researchers created human induced pluripotent stem cells that carry either the APOE3 or APOE4 gene in an …

… than the more common and risk-neutral APOE3 version, cells called oligodendrocytes mismanage cholesterol, failing … available , encompasses more than 160,000 individual cells of 11 different types from the prefrontal cortex of 32 … why, the team used patient-derived induced pluripotent stem cells to create lab cell cultures of oligodendrocytes …

… iPS Core Facility The advent of human induced pluripotent stem cells (iPSCs) has heralded a new generation of clinical and … into human disorders. Patient-derived skin fibroblast cells are reprogrammed into iPS cells, which allow …

… immune molecule called IL-17a, which is produced by immune cells during a fever, can temporarily reduce some of the … sciences, working with David Anderson. Anderson, a stem cell biologist, was switching his lab’s focus to …

… of brain tissue grown from human induced pluripotent stem cells.   “We have developed a 3D model of human myelination … aging and Alzheimer’s disease influence myelinating cells and neuronal health.” Using the cultures, he’ll be able …

… from cognition to cancer The nervous system regulates stem and precursor cell behavior across a range of tissues. … of healthy glial progenitors, oligodendrocyte precursor cells (OPCs), and the consequent generation of new … of neuronal activity on normal oligodendroglial precursor cells, a putative cellular origin for many forms of glioma, …

… cell types make appear immutable, but the influence those cells have over each other is flexible. The basolateral … Foundation, Alfred P. Sloan Foundation, New York Stem Cell Foundation and the National Institutes of Health …