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… if they knocked out the inhibitory cells’ endocannabinoid receptors then the place cells did a poorer job of … Fan will knock out the inhibitory cells’ endocannabinoid receptors and measure whether the place cells fail to show …

… obey it. They used a chemical tag to watch how key “AMPA” receptors changed in the synapses and saw that synaptic … with reduced amount of Arc were able to express more AMPA receptors whereas increased Arc in neighboring spines caused those synapses to express less AMPA receptors. “We think Arc maintains a balance of synaptic …

… to neural activity, that helps regulate the number of receptors for the neurotransmitter glutamate at excitatory … synapses or that decreased the proper cycling of glutamate receptors within synapses. The findings show how genetic …

… might require the molecular activation of their NMDA receptors. The lab had seen that knocking out the receptors across the visual cortex prevented the increase in … layers of the cortex but that it seemed to depend on NMDA receptors on a population of excitatory neurons in layer 6, …

… ganglia circuits. These deep brain circuits, which contain receptors that mediate the effects of cannabis, are known to … effects of cannabinoids. Her team recently found that CB1 receptors are tightly linked to dopamine — a neurotransmitter … a member of the McGovern Institute, will examine how CB1 receptors in the striatum, a deep brain structure implicated …

… recent work, Choi has been mapping immune system cytokine receptors across the whole mouse brain. That information has …

… neurons to communicate by disrupting the potassium ion receptors they use to regulate electric charge. Just a month … Heiman hypothesized that knocking out or blocking IL-6 receptors would therefore make Huntington’s disease model … overproduce the cytokine IL-17a. The molecule reaches receptors in the fetal brain. Cortical development in the …

… receptor, an initial member of a growing family of lipid receptors that includes S1P receptors that are targets for two current neuroscience … & siponimod for Multiple Sclerosis) with lysophospholipid receptors also linked to other diseases, including …