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… in the brain neurodegeneration myelination ApoE lipid metabolism epigenetics … Cognitive Sciences faculty. “We see convergence of lipid metabolism being disrupted, but when you really look into …

… which showed that APOE4-induced dysfunction of lipid metabolism in neurons by cellular accumulation of unsaturated … pathway in neuronal cells, thus stabilizing the lipid metabolism and concomitantly restoring normal cell function …

… mechanism: ferroptosis. This phenomenon, in which errant metabolism of iron leads to a lethal buildup of reactive …