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… In this way, neuromodulators can change the output of a circuit involved in a state or behavior. With appreciation of … TRH was an essential component in switching neural circuit activity in male mice, such that when they smelled … instance by broadly yet precisely influencing circuit activity to represent and switch among internal …

… was created to allow the Picower Institute to lead brain mapping microscopy methods to strategically make new advances …

… of specific mechanisms including preservation of neural circuit connections called synapses; a reduction in a cause … result is important, the researchers wrote, because neural circuit activity, which depends on maintaining synapses, is …

… with muscle (red) are highly informative models of neural circuit connections called "synapses." The Littleton lab … have been mapped out. A 3D rendering of a C. elegans worm, mapping all of its its neurons. C. elegans allows scientists … capable of tracking every behavior while simultaneously mapping the activity of every neuron) and employ a host of …

… release activates distinct receptor types throughout a circuit to change the large-scale activity patterns that give … and go well beyond to systematically achieve three aims: mapping out which combinations of serotonin receptors mediate …

… of sleep Sleep emerges from biochemical changes among circuit nodes or “nuclei” deep in the brain. Brown summarized … that sleep’s onset and cycles involve a “constellation” of circuit nuclei and brain chemicals. In a review in Science in … she wrote that the broad-based transformation of neural circuit activity during sleep likely represents the …

… April 11, 2022 Research Findings Innovative brain-wide mapping study shows that “engrams,” the ensembles of neurons … Innovative brain-wide mapping study shows that “engrams,” the ensembles of neurons … a graduate student in the RIKEN-MIT Laboratory for Neural Circuit Genetics at The Picower Institute led by senior …