… In Down syndrome cells, genome-wide disruptions mimic a senescence-like state … correct them in cell cultures. The study published in Cell Stem Cell therefore establishes senescence as a potentially … only by whether they had a third copy of chromosome 21. Stemcells derived from volunteers were cultured to turn into …
… A Picower Institute lab is on a mission to discover how cells mishandle lipid molecules in Alzheimer’s disease and is … lab took skin cells from donors and induced them to become stemcells. Then they turned those into three kinds of brain … focus on those cells came the next year in a study in Cell Stem Cell . There, Matheus Victor led the lab in discovering …
… goes awry in many diseases. airway-to-brain signaling stemcells neural systems As a newly named Pew Scholar in the … such as coughing, and repair responses that marshal stemcells to remodel damaged tissue. But in many diseases, …
… or “mini-brains.” To grow these cultures, a donor’s skin cells are reprogrammed to become induced pluripotent stemcells and those are then biochemically coaxed from that …
… Findings A breakdown of lipid metabolism in these brain cells promotes inflammation and interferes with neuron activity, a new study finds organoids iPSCs stemcells neurodegeneration ApoE lipid metabolism https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(22)00300-9 A breakdown of lipid …
