Neurotechnology

Picower Institute Neuroscientists don't just apply the latest technologies and methods for studying the brain, they also often invent them. To learn more about how researchers here work at, and expand, the frontiers of research, select them under Research Topics and you'll find relevant Picower people, discoveries and events.

Brady Weissbourd

Assistant Professor of Biology
Brady Weissbourd uses jellyfish to study nervous system evolution, development, regeneration, and function.

With Searle Scholar award, Fan will study serotonin role in memory

April 22, 2025
Picower People
Assistant Professor Linlin Fan will apply her lab’s precise “all-optical” techniques to study how serotonin might influence plasticity in memory, and whether psychedelics affect that.

MIT method enables ultrafast protein labeling of tens of millions of densely packed cells in organ-scale tissues

January 24, 2025
Research Findings
Tissue processing advance can label proteins at the level of individual cells across whole, intact rodent brains and other large samples just as fast and uniformly as in dissociated single cells.

Study suggests how the brain, with sleep, learns meaningful maps of spaces

December 10, 2024
Research Findings
Place cells are well known to encode individual locations, but new experiments and analysis indicate that stitching together a “cognitive map” of a whole environment requires a broader ensemble of cells, aided by sleep, to build a richer network over seve

Open technology platform enables new versatility for neuroscience research with more naturalistic behavior

November 13, 2024
Research Findings
System developed by MIT and Open Ephys team provides a fast, light, standardized means for combining multiple instruments with minimal hindrance of lab mouse mobility.

Research quantifying “nociception” could help improve management of surgical pain

September 23, 2024
Research Findings
New statistical models based on rigorous physiological data from more than 100 surgeries provide objective, accurate measures of “nociception,” the body’s subconscious perception of pain.

Fellowship enables study of how the brain makes memories of places

July 1, 2024
Picower People
With a new Klingenstein-Simons Fellowship in Neuroscience, Assistant Professor Linlin Fan will seek to strengthen understanding of how neural connections change to encode memories of specific locations.

Technologies enable 3D imaging of whole human brain hemispheres at subcellular resolution

June 13, 2024
Research Findings
A suite of three innovations by an MIT-based team enables high-throughput imaging of human brain tissue at a full range of scales and mapping connectivity of neurons at single cell resolution.

With programmable pixels, novel sensor improves imaging of neural activity

June 7, 2024
Research Findings
New camera chip design allows for optimizing each pixel’s timing to maximize signal to noise ratio when tracking real-time visual indicator of neural voltage

Microscope system sharpens scientists’ view of neural circuit connections

June 4, 2024
Research Findings
A newly described technology improves the clarity and speed of using two-photon microscopy to image synapses in the live brain

Plasticity and place: Study shows a key neural mechanism of remembering locations

March 25, 2024
Research Findings
Scientists have now observed how the brain’s place cells stave off inhibitory input in the process of establishing their tuning to specific locations. The study shows that signaling by endocannabinoids is required.

Livestreaming the Brain

March 15, 2024
Research Feature
To learn how the brain works, Picower Institute labs are advancing technologies and methods to watch it live as it happens