Research Topics

As this gallery of featured people and projects illustrates, Picower Institute scientists study brain structure and function at scales from genes and molecules to cells, circuits and regions. They also study the behaviors and cognitive processes that result, and seek to uncover how disruptions at different scales can result in developmental, psychiatric or neurodegenerative disorders. They employ—and often invent—the newest technologies in their work. To learn more about any of these specific areas, click "Research Topics" above, select areas of interest, and you'll find relevant Picower people, discoveries and events.

Li-Huei Tsai

Picower Professor of Neuroscience
The Tsai lab is interested in elucidating the pathogenic mechanisms underlying neurological disorders that impact learning and memory by taking a multidisciplinary approach to investigate the molecular, cellular, and circuit basis of neurodegenerative disorders.

Antidepressant restores youthful flexibility to aging inhibitory neurons in mice

August 20, 2018
Research findings
Neural plasticity, dendrite growth decline with age, study finds

Flavell earns School of Science named professorship

July 23, 2018
Tapped as the Lister Brothers Career Development Professor

Matt Wilson on Intelligence research at MIT

July 12, 2018
Q&A
From the Center for Brains Minds and Machines to the MIT Quest for Intelligence

The Developing Brain

July 11, 2018
News feature
Development research yields discoveries, insights, innovations

MIT scientists discover fundamental rule of brain plasticity

June 22, 2018
Research Findings
When a synapse strengthens, others immediately nearby weaken

Neuroscientists discover roles of gene linked to Alzheimer’s

May 31, 2018
Research Findings
Study reveals why people with the APOE4 gene have higher risk of the disease

Fighting toxic stress tough but possible, symposium speakers say

May 14, 2018
Events
'You have to really take the time to understand'

Brain circuit helps us learn by watching others

May 3, 2018
Research Findings
Scientists pinpoint neural interactions that are necessary for observational learning.

Symposium speaks to the many powers of brain rhythms

April 9, 2018
Events
11 experts convened at Picower April 4

Study IDs important role for specific gene in 16p11.2 deletion autism

March 20, 2018
Research Findings
Study finds MVP protein needed for homeostatic plasticity

Making waves for health

March 1, 2018
News feature
Innovative insights, methods raise clnical potential of instilling brain waves