Nanoparticle-delivered RNA reduces neuroinflammation in lab tests
In mice and human cell cultures, MIT researchers showed that novel nanoparticles can deliver a potential therapy for inflammation in the brain, a prominent symptom in Alzheimer’s disease
How a mutation in microglia elevates Alzheimer’s risk
A new MIT study finds that microglia with mutant TREM2 protein reduce brain circuit connections, promote inflammation and contribute to Alzheimer’s pathology in other ways
Anesthesia blocks sensation by cutting off communication within the cortex
Under propofol general anesthesia, sensory input still reaches the brain, but signals do not spread. Results suggest consciousness requires cortical regions to all be “on the same page.”
Award honors Elly Nedivi’s research on cortical plasticity
The Krieg Cortical Kudos Discoverer Award recognizes Nedivi’s ongoing work to understand molecular and cellular mechanisms that enable the brain to adapt to experience
New grant to study possibility of an immunotherapy for autism
Picower Institute-based collaboration will study mechanisms that might enable peripheral immune cells to deliver a potentially therapeutic molecule to the brain.
Aging Brain Initiative symposium showcases ‘cutting edge’ research across MIT
Seed projects, posters represent a wide range of labs working on technologies, therapeutic strategies, and fundamental research to advance understanding of age-related neurodegenerative disease
Anesthesia technology precisely controls unconsciousness in animal tests
An advanced closed-loop anesthesia delivery system that monitors brain state to tailor propofol dose and achieve exactly the desired level of unconsciousness could reduce post-op side effects
Society for Neuroscience Award recognizes Professor Mark Bear’s synaptic plasticity research, its translation to potential amblyopia and autism treatments, and his career of mentorship.
By analyzing epigenomic and gene expression changes that occur in Alzheimer’s disease, researchers identify cellular pathways that could become new drug targets