A saggital cross section of a mouse brain is richly stained in three distinct colors in three distinct areas: yellow in the very front and about halfway toward the back; green in a large area toward the front and cyan across wide areas, especially the cerebellum in the back
January 24, 2025
MIT method enables ultrafast protein labeling of tens of millions of densely packed cells in organ-scale tissues
Emery N. Brown stands in front of a wall. Superimposed on the image next to him is a picture of the front of the National Medal of Science, which depicts a man kneeling and drawing an abstract character in the ground next to him as he contemplates an object.
January 3, 2025
Emery N. Brown, innovative neuroscientist, statistician and anesthesiologist earns National Medal of Science
Two colorful arrays of dots are side by side. The left array, labeled session 1, is in a vaguely circular shape. The right array, labeled session 5, is in a structure similar to a sideways T, which is the actual shape of the maze that mice ran through.
December 10, 2024
Study suggests how the brain, with sleep, learns meaningful maps of spaces
A 3D cartoon of a mouse jumping around on a landscape of white hexagonal pillars. The mouse's trajectory through time is noted with a wiggly blue line. The mouse wears electronics on the back of its head and a small thin wire comes up out of them.
November 13, 2024
Open technology platform enables new versatility for neuroscience research with more naturalistic behavior
A cartoon shows a head in profile split between a gray region at the front and a green region at the back. In the back is a bell and progressively larger dotted white circles propagate outward from the bell toward the front of the head.
October 7, 2024
The way sensory prediction changes under anesthesia tells us how conscious cognition works

From molecular to whole-brain scale in a simple animal, study reveals serotonin’s effects

May 15, 2023
Research Findings
With full genetic control and visibility into neural activity and behavior, MIT scientists map out chemical’s role in behavior

Neuroscientists identify cells especially vulnerable to Alzheimer’s

April 19, 2023
Research Findings
Neurons that form part of a memory circuit are among the first brain cells to show signs of neurodegeneration in Alzheimer’s disease.

A new peptide may hold potential as an Alzheimer’s treatment

April 12, 2023
Research Findings
The peptide blocks a hyperactive brain enzyme that contributes to the neurodegeneration seen in Alzheimer’s and other diseases.

Fluid flow in the brain can be manipulated by sensory stimulation

April 10, 2023
Research Findings
Blood flow induced by visual stimulation drives the flow of cerebrospinal fluid

Studying consciousness without affecting it

April 6, 2023
Research Findings
A new study tests an alternative to external stimulation for measuring when subjects lose and regain responsiveness during sedation and anesthesia.

Spring break tours give high schoolers a chance to see science up close

March 31, 2023
Picower Events
Teens from area high schools got the chance to learn about advanced biology and brain research on field trips to MIT

‘Spatial Computing’ enables flexible working memory

March 15, 2023
Research Findings
Brain applies rhythms to physical patches of the cortex to selectively control just the right neurons at the right times to do the right things.

3 questions for Mriganka Sur: The basic research origin of the first approved drug to treat Rett syndrome

March 10, 2023
On March 10 the FDA approved Trofinetide, a drug based on the protein IGF-1, as the first drug available to treat Rett syndrome. The original research showing that IGF-1 could treat Rett syndrome was published by MIT in 2009.

Astrocyte cells critical for learning skilled movements

March 10, 2023
Research Findings
When astrocyte function is disrupted, neurons in the brain’s motor cortex struggle to execute and refine motion, a new study in mice shows.

Immune & Inflamed

March 1, 2023
Research Feature
Neuroscientists are finding that immune system activity within the brain and the body has important impacts on mental health and behavior

Picower Fellows discuss the social context of their science

February 14, 2023
Picower People
Young neuroscientists contributed their perspectives as the MIT Museum works to create a potential ‘Center for Neuroscience & Society’

Researchers map brain cell changes in Alzheimer’s disease

February 2, 2023
Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue