Li-Huei Tsai stands at a podium embossed with an MIT logo. In the foreground is an attentive audience. In the background is the Picower Institute logo
March 11, 2026
After 16+ years leading Picower Institute, Li-Huei Tsai will sharpen focus on research, teaching
Two panels show blue cells surrounded by thin green outlines. The outlines are much more consistent and prevalent in the image on the left, which is labeled as the wild type, than on the right which is labeled Rett syndrome.
February 25, 2026
In Rett syndrome, leaky brain blood vessels traced to microRNA
a series of small blocky spots of color appear in the aggregate to make up the shape of a worm as it stretches horizonally across a black background
February 24, 2026
As worms and jellyfish wriggle, new AI tools track their neurons
Linlin Fan stands in her lab with microscope equipment in the foreground.
February 17, 2026
Sloan Fellowship will help Fan advance technology to study how brain circuits change amid learning
Wearing white lab coats in the lab, Mark Bear stands behind Sara Kornfeld-Sylla as she sits in a stool at a lab bench
February 11, 2026
Fragile X study uncovers brainwave biomarker bridging humans and mice

Study may explain how infections reduce autism symptoms

December 18, 2019
Research Findings
An immune molecule sometimes produced during infection can influence the social behavior of mice.

Human Models of Disease

December 16, 2019
News Feature
Stem cell, genetic technologies enable sophisticated studies of human brain cells and brain "organoids"

Study probing visual memory, amblyopia unveils many-layered mystery

December 13, 2019
Research Findings
Plasticity underlying amblyopia found in visual cortex layer 4

Scientists eager to explain brain rhythm boost’s broad impact in Alzheimer’s models

December 9, 2019
Research findings
Paper lays out new areas of investigation

Tsai elected fellow of National Academy of Inventors

December 3, 2019
Picower People
Honor notes innovations in research addressing Alzheimer’s disease

Down syndrome symposium highlights potential progress at many scales

November 14, 2019
Events
The inaugural symposium of the Alana Down Syndrome Center

Picower scientists shine in Chicago at 'SfN'

October 28, 2019
News Feature
About 50 institute researchers presented talks and posters over 5 days

In Alzheimer’s research, MIT scientists reveal brain rhythm role

October 22, 2019
At 'SFN'
At Society for Neuroscience meeting, Li-Huei Tsai presents latest findings on sensory stimulation of gamma rhythm

Fundamental questions find advanced answers, approaches at Fall Symposium

October 18, 2019
Events
Experts from around the world discuss "Neural Mechanisms of Memory and Cognition"

Memory and its meaning

October 7, 2019
News Feature
25 Years of Picower Institute research

Study pinpoints Alzheimer’s plaque emergence early and deep in the brain

October 4, 2019
Research findings
Amyloid emerges early in deep regions such as the mammillary body and marches outward along specific circuits

MIT sets out to model Alzheimer’s disease complexity on a chip

October 3, 2019
New Research
Integrating patient-derived brain cell types with vasculature, computer models will yield powerful research platform