Neurons glow green against a black background in a section of a mouse brain. A few red specks can be seen. An inset magnifies one of these cells that has red and green staining.
April 28, 2025
Dopamine signals when a fear can be forgotten
A 2 by 2 array of panels that each show a hairpin-like shape of blue stained cells. The left column is laberled "Ambient light/sound." The right column is labeled "40Hz Stimulation." The panels in the 40Hz column show more yellow arrows pointing white blotches than the panels in the ambient column.
April 24, 2025
In Down syndrome mice, 40Hz light and sound improve cognition, neurogenesis, connectivity
Emery Brown sits behind his desk in his MIT office. A teddy bear rests nestled among some books on a shelf behind him, just over his right shoulder.
April 21, 2025
In kids, EEG monitoring of consciousness safely reduces anesthetic use
In a grayscale image a wiggly worm is seen in a vertical orientation above a lumpy background of bacteria
April 8, 2025
A simple animal’s response to sickness highlights the nervous system’s surprising degrees of flexibility
A black brain shown in a side view glows blue. The amygdala, a small almond-shaped structure toward the bottome center stands out especially. In the background there are theater masks signifying emotions.
April 7, 2025
Molecules that fight infection also act on the brain, inducing anxiety or sociability

Aging Brain Initiative awards fund 5 new ideas to study, fight neurodegeneration

April 20, 2022
New Research
Competitive seed grants launch yearlong investigations of novel hypotheses about potential causes, biomarkers, treatments of Alzheimer’s and ALS.

A single memory is stored across many connected brain regions

April 11, 2022
Research Findings
Innovative brain-wide mapping study shows that “engrams,” the ensembles of neurons encoding a memory, are widely distributed, including among regions not previously realized

Emery Brown earns AIMBE’s highest honor

March 25, 2022
Picower People
Pierre Galletti Award recognizes contributions to neural signal processing, anesthesiology advances

The model remodeler

March 14, 2022
Research Feature
A Picower Institute primer on ‘plasticity,’ the brain’s amazing ability to constantly adapt to and learn from experience

Neurons are fickle. Electric fields are more reliable for information.

March 14, 2022
Research Findings
A new study suggests that electric fields may represent information held in working memory, allowing the brain to overcome “representational drift,” or the inconsistent participation of individual neurons

Mriganka Sur elected to the 2022 class of the AIMBE College of Fellows

February 28, 2022
Picower People
National Institute recognizes innovations and research elucidating neuronal plasticity and computations

A new “atlas” of cells that carry blood to the brain

February 14, 2022
Research Findings
Single-cell gene expression analyses of human cerebrovascular cells can help reveal new drug targets for Huntington’s disease and other neurodegenerative diseases.

Research advances technology of AI assistance for anesthesiologists

February 2, 2022
Research Findings
A new deep learning algorithm trained to optimize doses of propofol to maintain unconsciousness during general anesthesia could augment patient monitoring

‘Traveling’ nature of brain waves may help working memory work

January 31, 2022
Research Findings
The act of holding information in mind is accompanied by coordination of rotating brain waves in the prefrontal cortex, a new study finds.

Next-generation tissue expansion method improves neural imaging

January 13, 2022
Research Findings
An upgrade of ‘MAP’ enables labeling of more proteins, deeper studies of circuit junctions in brain tissue

In Down syndrome cells, genome-wide disruptions mimic a senescence-like state

January 6, 2022
Research Findings
Extra chromosome alters chromosomal conformation and DNA accessibility across the whole genome in neural progenitor cells, disrupting gene transcription and cell functions much like in cellular aging.

'Risky' Research

December 20, 2021
Research Feature
How bold new neuroscience research projects get off the ground