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A complete rethinking of how our brains use categories to make sense of the world

April 13, 2026
Research Findings
Challenging the classic view, two cognitive scientists argue in a new review that categorization is not a late, specialized stage of sensory processing. Instead, it is a core function operating at every level, anticipating bodily needs and motor plans.

With navigating nematodes, scientists map out how brains implement behaviors

April 10, 2026
Research Findings
How do nervous systems produce behaviors? A new MIT study provides a detailed mechanistic mapping of exactly what happens in the brains of C. elegans worms when they “follow their nose” to savor attractive odors or avoid unappealing ones

Leading with rigor, kindness, and care

April 2, 2026
Picower People
“We cannot be effective scientists if we are unhappy or unhealthy outside of the lab,” says “Committed to Caring” honoree Sara Prescott.

Brain Simulation

March 23, 2026
Research Feature
Picower Institute researchers and collaborators are inventing versatile new models of the brain to accelerate neuroscience discoveries and biomedical advances.

Three anesthesia drugs all have the same effect in the brain, MIT researchers find

March 17, 2026
Research Findings
Discovering this common mechanism could lead to a universal anesthesia-delivery system to monitor patients more effectively.

After 16+ years leading Picower Institute, Li-Huei Tsai will sharpen focus on research, teaching

March 11, 2026
Picower People
Tsai, who has grown the MIT neuroscience institute, will increase focus on research including Alzheimer’s disease and Down syndrome

In Rett syndrome, leaky brain blood vessels traced to microRNA

February 25, 2026
Research Findings
MIT neuroscientists have found that either of two genetic mutations that cause Rett syndrome undermine the structural integrity of developing blood vessels. By showing that the problem derives from overexpression of a microRNA, the new study points to a p

As worms and jellyfish wriggle, new AI tools track their neurons

February 24, 2026
Research Findings
Three new neural network-based tools enable fast, accurate alignment and annotation of images even in very wiggly subjects. The tools might offer a way to automate cell tracking in other imaging datasets, too.

Sloan Fellowship will help Fan advance technology to study how brain circuits change amid learning

February 17, 2026
Picower People
Linlin Fan uses innovative optical tools to precisely investigate how connections change among neurons during memory formation. With Sloan Foundation support, she plans to give the technology a significant upgrade

Fragile X study uncovers brainwave biomarker bridging humans and mice

February 11, 2026
Research Findings
A collaboration centered at MIT discovered that mice modeling the autism spectrum disorder fragile X syndrome exhibit the same pattern of differences in low-frequency waves as human patients, identifying a new biomarker for treatment studies

Opening a new window on the brainstem, AI algorithm enables tracking of its vital white matter pathways

February 6, 2026
Research Findings
Filled with vitally important neural fibers, the brainstem has been hard for brain imaging technologies to dissect. New software reliably and finely resolves eight distinct nerve bundles in live diffusion MRI scans, revealing signs of injury or disease

How a unique class of neurons may set the table for brain development

January 14, 2026
Research Findings
A new MIT study finds that somatostatin-expressing neurons follow a unique trajectory when forming connections in the brain’s visual cortex that may help establish the conditions needed for sensory experience to refine circuits.