New statistical models based on rigorous physiological data from more than 100 surgeries provide objective, accurate measures of “nociception,” the body’s subconscious perception of pain.

Studying neuromodulators such as serotonin and norepinephrine could help make them better targets for psychiatric or psychedelic drugs

Every year members of The Picower Institute find they can explore new ideas and interactions by experiencing the change of scenery afforded by the Dana and Betty Fisher retreat

In awake mice, researchers found that even low stimulation currents could sometimes still cause electrographic seizures

Two teens who spent their summer in Picower Institute labs via MIT outreach programs gained exposure to neuroscience they can carry with them to college

MIT scientists report that gamma frequency light and sound stimulation preserves myelination in mouse models and reveal molecular mechanisms that may underlie the benefit.

A new mathematical method, validated with experimental animal data, provides a fast, reliable and minimally invasive way of determining how to treat critical blood pressure changes during surgery or intensive care.

Genomics and lab studies reveal numerous findings, including a key role for Reelin amid neuronal vulnerability, and for choline and antioxidants in sustaining cognition.

In animals from worms to humans, feelings and drives such as hunger or sleepiness influence behavior. With flexible, long-term support as a newly named HHMI Investigator, Steve Flavell will advance his lab’s studies of exactly how that happens.

Propofol, a drug commonly used for general anesthesia, derails the brain’s normal balance between stability and excitability.

With strong personal motivation and up to three years of support from the HHMI Gilliam Fellows Program, graduate student Mingus Rae Zoller will probe mysteries of Alzheimer’s and its possible treatment.

With an eye on implications for regenerative medicine, Assistant Professor Brady Weissbourd will use the support of being named a Searle Scholar to study how jellyfish excel at building and regenerating their neural networks.