Cultured from induced pluripotent stem cells, ‘miBrains’ integrate all major brain cell types and model brain structures, cellular interactions, activity, and pathological features.

MIT neuroscientists show in a new study that loops of RNA can strongly influence how neurons build circuit connections, or synapses, during the development of the visual system in young mice.

By carefully tracking the formation and maturation of synaptic active zones in fruit flies, MIT scientists have discovered how neural activity helps circuit connections become tuned to the right size and degree of signal transmission

Picower Institute studies reveal a number of ways moods emerge in the brain and therefore many potential paths to address depression, PTSD, anxiety and bipolar disorder.

Before a packed house, speakers at MIT’s Aging Brain Initiative symposium described how immune system factors during aging contribute to Alzheimer’s, Parkinson’s and other conditions. The field is leveraging that knowledge to develop new therapies

As an object moves across your field of view, the brain seamlessly hands off visual processing from one hemisphere to the other like cell phone towers or relay racers do, a new MIT study shows.

Lipid metabolism and cell membrane function can be disrupted in the neurons of people who carry rare variants of ABCA7.

Study of 3.5 million cells from more than 100 human brains finds that Alzheimer’s progression—but also resilience to disease—depends on preserving epigenomic stability.

By combining several cutting-edge imaging technologies, a new microscope system could enable unprecedentedly deep and precise visualization of metabolic and neuronal activity, potentially even in humans.

MIT researchers employed a novel application of tools and analysis to show that astrocytes ensure neural information processing by maintaining ambient levels of the neurotransmitter chemical GABA.

For undergraduates around the country who are interested in studying neuroscience but don't have enough opportunities at their home institutions, Picower Institute labs can provide a way to do cutting edge research and gain exposure to a possible future i

A first-of-its-kind study in mice reveals that neurons add and shed synapses at a frenzied pace during development to integrate visual signals from the two eyes.