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Massachusetts Institute of Technology
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Cambridge, MA 02139
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You searched for: striatum

Research highlights immune molecule’s complex role in Huntington’s disease

Tuesday, May 26
… from a prior study, green staining highlights Stat3 in the striatum region of the brain. Stat3 is a major transducer of … gene expression in all the major cell types in the striatum, the brain region most affected in HD, by sequencing …
https://picower.mit.edu/node/656

Circuit model may explain how deep brain stimulation treats Parkinson’s disease symptoms

Monday, May 16
… ability of interneurons to regulate rhythms in the brain’s striatum, improving movement, study suggests striatum deep brain stimulation Dopamine neurodegeneration … ability of interneurons to regulate rhythms in the brain’s striatum, improving movement, study suggests People with …
https://picower.mit.edu/node/920

Genetic screen offers new drug targets for Huntington’s disease

Thursday, Jan 30
… identify genes that modulate the disease’s toxic effects striatum Huntington's Disease CRISPR/Cas9 neurodegeneration … highly concentrated, and to inject them directly into the striatum of the brain. Using this approach, they were able to … elements to about 25 percent of all of the cells in the striatum. The researchers focused on the striatum, which is …
https://picower.mit.edu/node/613

MIT biologists discover an unusual hallmark of aging in neurons

Tuesday, Nov 27
… interfere with normal function TRAP mRNA neuronal identity striatum prefrontal cortex … human brains, especially in a part of the brain called the striatum — a site involved in diseases such as Parkinson’s … which make up 95 percent of the neurons found in the striatum. They labeled these cells in younger mice (6 weeks …
https://picower.mit.edu/node/436

Studies help explain link between autism, severe infection during pregnancy

Wednesday, Sep 13
… the temporal association area of the cortex and the striatum. When the researchers inhibited the neurons … deficits. When they inhibited the neurons connected to the striatum, they were able to halt the repetitive behaviors. …
https://picower.mit.edu/node/458

Neural networks need more than neurons, new project posits

Thursday, Mar 04
… to carry out exploration and guide cells in the brain’s striatum to execute exploitation. The collaboration will … she studies reinforcement learning and its roots in the striatum. Meanwhile Sur and Alfonoso Araque at Minnesota will …
https://picower.mit.edu/node/764

Neural vulnerability in Huntington’s disease tied to release of mitochondrial RNA

Friday, Jul 17
… neuroimmunology Huntington's Disease aging mRNA TRAP striatum … disease, lead to damage in a brain region called the striatum, Heiman said. In a condition called …
https://picower.mit.edu/node/679

Aging Brain Initiative awards fund 5 new ideas to study, fight neurodegeneration

Wednesday, Apr 20
… neurodegeneration neuroimmunology Neuroimmune interactions striatum Artificial Intelligence Competitive seed grants … early emergence of Alzheimer’s disease pathology in the striatum. That’s a a brain region crucial for motivation and …
https://picower.mit.edu/node/910

Picower Research and Artificial Intelligence

… of learning-related activity in the prefrontal cortex and striatum LTP and LTD: An embarrassment of riches Off Off … …
https://picower.mit.edu/node/700

Deep stimulation improves cognitive control by augmenting brain rhythms

Thursday, Apr 04
… to the brain’s ventral internal capsule and ventral striatum (VCVS) has shown mixed results in treating OCD and …
https://picower.mit.edu/node/502

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Massachusetts Institute of Technology
43 Vassar Street, Bldg. 46-1303
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(+1) 617-324-0305
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